1-tert-butyl 4-ethyl 4-(trifluoromethyl)piperidine-1,4-dicarboxylate

Base Information

Chemical Name:1-tert-butyl 4-ethyl 4-(trifluoromethyl)piperidine-1,4-dicarboxylate
CAS No.:1255099-09-2
Molecular Formula:C14H22F3NO4
Molecular Weight:325.32
Hs Code.:
Mol file:1255099-09-2.mol

Synonyms:1-tert-butyl 4-ethyl 4-(trifluoromethyl)piperidine-1,4-dicarboxylate

Suppliers and Price of 1-tert-butyl 4-ethyl 4-(trifluoromethyl)piperidine-1,4-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
1-tert-Butyl4-ethyl4-(trifluoromethyl)piperidine-1,4-dicarboxylate
1g
$ 1049.67

Total 5 raw suppliers

Chemical Property of 1-tert-butyl 4-ethyl 4-(trifluoromethyl)piperidine-1,4-dicarboxylate

Chemical Property:

PSA：55.84000
LogP:3.06700

Purity/Quality:

97% ^*data from raw suppliers

1-tert-Butyl4-ethyl4-(trifluoromethyl)piperidine-1,4-dicarboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-tert-butyl 4-ethyl 4-(trifluoromethyl)piperidine-1,4-dicarboxylate

There total 3 articles about 1-tert-butyl 4-ethyl 4-(trifluoromethyl)piperidine-1,4-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: Umemoto's reagent

: 142851-03-4
1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate

: 1255099-09-2
1-tert-butyl 4-ethyl 4-(trifluoromethyl)piperidine-1,4-dicarboxylate

Guidance literature:: 1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;

Umemoto's reagent; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 24h;
DOI:10.1021/jacs.1c09066

Reference yield: 23.0%

: 129946-88-9
Umemoto's reagent

: 142851-03-4
1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate

: 1255099-09-2
1-tert-butyl 4-ethyl 4-(trifluoromethyl)piperidine-1,4-dicarboxylate

Guidance literature:: 1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.75h;

Umemoto's reagent; In tetrahydrofuran; at -78 - 20 ℃; for 6h;