tert-Butyl 6-bromo-3,4-dihydroquinoline-1(2H)-carboxylate

Base Information

Chemical Name:tert-Butyl 6-bromo-3,4-dihydroquinoline-1(2H)-carboxylate
CAS No.:1123169-45-8
Molecular Formula:C14H18BrNO2
Molecular Weight:312.20222
Hs Code.:2933499090
DSSTox Substance ID:DTXSID90696254
Mol file:1123169-45-8.mol

Synonyms:1123169-45-8;tert-Butyl 6-bromo-3,4-dihydroquinoline-1(2H)-carboxylate;1-BOC 6-bromo-3,4-dihydro-2H-quinoline;6-BROMO-3,4-DIHYDRO-2H-QUINOLINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;tert-butyl 6-bromo-3,4-dihydro-2H-quinoline-1-carboxylate;MFCD11858570;t-Butyl 6-bromo-3,4-dihydro-2H-quinoline-1-carboxylate;tert-butyl 6-bromo-1,2,3,4-tetrahydroquinoline-1-carboxylate;N-Boc-6-bromo-dihydroquinoline;SCHEMBL15616589;DTXSID90696254;tert-Butyl6-bromo-3,4-dihydroquinoline-1(2H)-carboxylate;AKOS015897221;SB30739;AS-39185;SY239853;CS-0060939;FT-0755186;1-Boc-6-bromo-1,2,3,4-tetrahydroquinoline;EN300-316297;A894608

Suppliers and Price of tert-Butyl 6-bromo-3,4-dihydroquinoline-1(2H)-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynChem
1-BOC 6-bromo-3,4-dihydro-2H-quinoline 95%
1 g
$ 150.00

J&W Pharmlab
6-Bromo-3,4-dihydro-2H-quinoline-1-carboxylicacidtert-butylester 97%
25g
$ 465.00

Crysdot
tert-Butyl6-bromo-3,4-dihydroquinoline-1(2H)-carboxylate 95+%
5g
$ 317.00

Crysdot
tert-Butyl6-bromo-3,4-dihydroquinoline-1(2H)-carboxylate 95+%
25g
$ 1194.00

Crysdot
tert-Butyl6-bromo-3,4-dihydroquinoline-1(2H)-carboxylate 95+%
10g
$ 624.00

ChemScene
tert-Butyl6-bromo-3,4-dihydroquinoline-1(2H)-carboxylate >98.0%
1g
$ 55.00

ChemScene
tert-Butyl6-bromo-3,4-dihydroquinoline-1(2H)-carboxylate >98.0%
5g
$ 265.00

ChemScene
tert-Butyl6-bromo-3,4-dihydroquinoline-1(2H)-carboxylate >98.0%
10g
$ 508.00

Chemenu
6-Bromo-3,4-dihydro-2H-quinoline-1-carboxylicacidtert-butylester 95%
10g
$ 486.00

Chemenu
6-Bromo-3,4-dihydro-2H-quinoline-1-carboxylicacidtert-butylester 95%
5g
$ 281.00

Total 23 raw suppliers

Chemical Property of tert-Butyl 6-bromo-3,4-dihydroquinoline-1(2H)-carboxylate

Chemical Property:

Boiling Point:382.0±41.0 °C(Predicted)
PKA:0.02±0.20(Predicted)
PSA：29.54000
Density:1.353±0.06 g/cm3(Predicted)
LogP:4.20180
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:311.05209
Heavy Atom Count:18
Complexity:313

Purity/Quality:

97% ^*data from raw suppliers

1-BOC 6-bromo-3,4-dihydro-2H-quinoline 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCCC2=C1C=CC(=C2)Br

Technology Process of tert-Butyl 6-bromo-3,4-dihydroquinoline-1(2H)-carboxylate

There total 1 articles about tert-Butyl 6-bromo-3,4-dihydroquinoline-1(2H)-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 22190-35-8
6-bromo-1,2,3,4-tetrahydroquinoline

: 24424-99-5
di-tert-butyl dicarbonate

: 1123169-45-8
tert-butyl 6-bromo-3,4-dihydroquinoline-1(2H)-carboxylate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃;
DOI:10.1002/cmdc.201800242

Reference yield: 94.0%

: 1123169-45-8
tert-butyl 6-bromo-3,4-dihydroquinoline-1(2H)-carboxylate

: 100-53-8
phenylmethanethiol

: tert-butyl 6-(benzylthio)-3,4-dihydroquinoline-2(1H)-carboxylate

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; N-ethyl-N,N-diisopropylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; at 100 ℃; for 6h; Inert atmosphere;
DOI:10.1002/cmdc.201800242

Reference yield: 94.0%

: 1123169-45-8
tert-butyl 6-bromo-3,4-dihydroquinoline-1(2H)-carboxylate

: 73183-34-3
bis(pinacol)diborane

: 1912446-60-6
tert-butyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinoline-1(2H)-carboxylate

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; In 1,4-dioxane; water; at 100 ℃; Inert atmosphere;