5,7-Dihydroxy-3-(2,4,5-trimethoxyphenyl)chromen-4-one

Base Information

Chemical Name:5,7-Dihydroxy-3-(2,4,5-trimethoxyphenyl)chromen-4-one
CAS No.:75340-02-2
Molecular Formula:C18H16O7
Molecular Weight:344.31544
Hs Code.:
DSSTox Substance ID:DTXSID301177865
Nikkaji Number:J997.728G
Wikidata:Q104401195
Metabolomics Workbench ID:121888
ChEMBL ID:CHEMBL1087519
Mol file:75340-02-2.mol

Synonyms:7-demethylrobustigenin;75340-02-2;5,7-dihydroxy-3-(2,4,5-trimethoxyphenyl)chromen-4-one;MEGxp0_001809;CHEMBL1087519;DTXSID301177865;FT-0696053;5,7-Dihydroxy-2',4',5'-trimethoxyisoflavone;5,7-Dihydroxy-2/',4/',5/'-trimethoxyisoflavone;5,7-Dihydroxy-3-(2,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one

Suppliers and Price of 5,7-Dihydroxy-3-(2,4,5-trimethoxyphenyl)chromen-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-Demethylrobustigenin
25mg
$ 1320.00

Total 3 raw suppliers

Chemical Property of 5,7-Dihydroxy-3-(2,4,5-trimethoxyphenyl)chromen-4-one

Chemical Property:

PSA：98.36000
LogP:2.89700
XLogP3:2.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:344.08960285
Heavy Atom Count:25
Complexity:520

Purity/Quality:

99% ^*data from raw suppliers

7-Demethylrobustigenin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C(C=C1C2=COC3=CC(=CC(=C3C2=O)O)O)OC)OC
Uses 7-Demethylrobustigenin is a flavonoid compound present in plants, specifically, Erythrina Sacleuxil which shows antiplasmodial activities.

Technology Process of 5,7-Dihydroxy-3-(2,4,5-trimethoxyphenyl)chromen-4-one

There total 7 articles about 5,7-Dihydroxy-3-(2,4,5-trimethoxyphenyl)chromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 72545-40-5
2',4',6'-trihydroxy-(2,4,5-trimethoxyphenyl)acetophenone

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 75340-02-2
5,7-dihydroxy-3-(2,4,5-trimethoxyphenyl)chromen-4-one

Guidance literature:: With boron trifluoride diethyl etherate; methanesulfonyl chloride; at 20 - 90 ℃; for 3.83333h;
DOI:10.1002/ejoc.201201339

Reference yield:

: 75340-01-1
5,7-bis(benzyloxy)-2',4',5'-trimethoxyisoflavone

: 75340-02-2
5,7-dihydroxy-3-(2,4,5-trimethoxyphenyl)chromen-4-one

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; Ambient temperature;
DOI:10.1246/bcsj.53.831

Reference yield:

: 75340-00-0
4,6-bis(benzyloxy)-2-hydroxy-2',4',5'-trimethoxydeoxybenzoin

: 75340-02-2
5,7-dihydroxy-3-(2,4,5-trimethoxyphenyl)chromen-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 200 mg / Na / 12 h / Ambient temperature

2: 110 mg / H₂ / 10percent Pd/C / ethyl acetate / Ambient temperature

With hydrogen; sodium; palladium on activated charcoal; In ethyl acetate;
DOI:10.1246/bcsj.53.831