4'-METHOXY-3-(2-METHOXYPHENYL)PROPIOPHENONE

Base Information

• Chemical Name: 4'-METHOXY-3-(2-METHOXYPHENYL)PROPIOPHENONE
• CAS No.: 109089-84-1
• Molecular Formula: C17H18O3
• Molecular Weight: 270.328
• Hs Code.: 2914509090
• Mol file: 109089-84-1.mol

Synonyms:4'-METHOXY-3-(2-METHOXYPHENYL)PROPIOPHENONE

Chemical Property of 4'-METHOXY-3-(2-METHOXYPHENYL)PROPIOPHENONE

Chemical Property:

• Vapor Pressure: 1.67E-07mmHg at 25°C
• Boiling Point: 427.2°C at 760 mmHg
• Flash Point: 203.9°C
• PSA: 35.53000
• Density: 1.098g/cm³
• LogP: 3.51930

Purity/Quality:

98%min ^*data from raw suppliers

4'-Methoxy-3-(2-methoxyphenyl)propiophenone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4'-METHOXY-3-(2-METHOXYPHENYL)PROPIOPHENONE

There total 7 articles about 4'-METHOXY-3-(2-METHOXYPHENYL)PROPIOPHENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(2-methoxyphenyl)methanol (612-16-8) + 1-(4-methoxyphenyl)ethanone (100-06-1) → 3-(2-methoxyphenyl)-1-(4-methoxyphenyl)propan-1-one (109089-84-1)

Guidance literature:

With bis(1,5-cyclooctadiene)diiridium(I) dichloride; triphenylphosphine; potassium hydroxide; at 100 ℃; for 6h; Inert atmosphere; Sealed tube;

DOI:10.1002/anie.201410391

Reference yield: 63.0%

rac-1-(4-methoxyphenyl)-ethanol (3319-15-1) + (2-methoxyphenyl)methanol (612-16-8) → 3-(2-methoxyphenyl)-1-(4-methoxyphenyl)propan-1-one (109089-84-1)

Guidance literature:

With potassium hydroxide; In toluene; at 110 ℃; for 24h; Inert atmosphere; Green chemistry;

Reference yield:

(E)-1-(4-methoxylphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one (39188-79-9,55210-76-9) → 3-(2-methoxyphenyl)-1-(4-methoxyphenyl)propan-1-one (109089-84-1)

Guidance literature:

With methanol; platinum; Hydrogenation;

DOI:10.1039/jr9580004302

upstream raw materials:

3-(2-methoxyphenyl)propionyl chloride

methoxybenzene

(E)-1-(4-methoxylphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one

2-hydroxy-4-methoxy-trans(?)-chalcone

Downstream raw materials:

3-(2-methoxy-phenyl)-1-(4-methoxy-phenyl)-propan-1-ol

Refernces

• 1、 Seck, Charlotte,Mbaye, Mbaye Diagne,Coufourier, Sébastien,Lator, Alexis,Lohier, Jean-Fran?ois,Poater, Albert,Ward, Thomas R.,Gaillard, Sylvain,Renaud, Jean-Luc. "Alkylation of Ketones Catalyzed by Bifunctional Iron Complexes: From Mechanistic Understanding to Application". . p. 4410 - 4416. Retrieved 2017/11/20.
• 2、 Shen, Di,Poole, Darren L.,Shotton, Camilla C.,Kornahrens, Anne F.,Healy, Mark P.,Donohoe, Timothy J.. "Hydrogen-borrowing and interrupted-hydrogen-borrowing reactions of ketones and methanol catalyzed by iridium". supporting information. p. 1642 - 1645. Retrieved 2015/02/05.