4'-Phenyl-2,2,2-trifluoroacetophenone

Base Information

Chemical Name:4'-Phenyl-2,2,2-trifluoroacetophenone
CAS No.:2369-31-5
Molecular Formula:C14H9F3O
Molecular Weight:250.22
Hs Code.:2914700090
DSSTox Substance ID:DTXSID30454734
Nikkaji Number:J880.832E
Wikidata:Q82276432
Mol file:2369-31-5.mol

Synonyms:2369-31-5;4'-PHENYL-2,2,2-TRIFLUOROACETOPHENONE;1-([1,1'-Biphenyl]-4-yl)-2,2,2-trifluoroethanone;2,2,2-trifluoro-1-(4-phenylphenyl)ethanone;2,2,2-TRIFLUORO-1-(4-PHENYLPHENYL)ETHAN-1-ONE;MFCD01320014;1-([1,1'-biphenyl]-4-yl)-2,2,2-trifluoroethan-1-one;1-{[1,1'-biphenyl]-4-yl}-2,2,2-trifluoroethan-1-one;4-(TRIFLUOROACETYL)BIPHENYL;SCHEMBL4502846;DTXSID30454734;RRQMTKLKELCWIL-UHFFFAOYSA-N;AKOS014791008;AB08984;1-Biphenyl-4-yl-2,2,2-trifluoroethanone;CS-0269810;2,2,2-Trifluoro-1-(biphenyl-4-yl)ethanone;EN300-1871657

Suppliers and Price of 4'-Phenyl-2,2,2-trifluoroacetophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Rieke Metals
4'-Phenyl-2,2,2-trifluoroacetophenone 97%
5g
$ 1059.00

Rieke Metals
4'-Phenyl-2,2,2-trifluoroacetophenone 97%
2g
$ 516.00

Rieke Metals
4'-Phenyl-2,2,2-trifluoroacetophenone 97%
1g
$ 340.00

Oakwood
4'-Phenyl-2,2,2-trifluoroacetophenone 97%
1g
$ 357.00

Oakwood
4'-Phenyl-2,2,2-trifluoroacetophenone 97%
250mg
$ 160.00

Matrix Scientific
4'-Phenyl-2,2,2-trifluoroacetophenone 97%
5g
$ 989.00

Matrix Scientific
4'-Phenyl-2,2,2-trifluoroacetophenone 97%
2g
$ 513.00

Matrix Scientific
4'-Phenyl-2,2,2-trifluoroacetophenone 97%
1g
$ 359.00

Crysdot
1-([1,1'-Biphenyl]-4-yl)-2,2,2-trifluoroethanone 95+%
1g
$ 305.00

Crysdot
1-([1,1'-Biphenyl]-4-yl)-2,2,2-trifluoroethanone 95+%
5g
$ 839.00

Total 10 raw suppliers

Chemical Property of 4'-Phenyl-2,2,2-trifluoroacetophenone

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Melting Point:102.5-103.5 °C(Solv: methanol (67-56-1))
Boiling Point:309.928°C at 760 mmHg
Flash Point:153.229°C
PSA：17.07000
Density:1.235g/cm³
LogP:4.09860
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:250.06054939
Heavy Atom Count:18
Complexity:284

Purity/Quality:

98%min ^*data from raw suppliers

4'-Phenyl-2,2,2-trifluoroacetophenone 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)C(F)(F)F

Technology Process of 4'-Phenyl-2,2,2-trifluoroacetophenone

There total 4 articles about 4'-Phenyl-2,2,2-trifluoroacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

: 431-47-0
trifluoroacetic acid-methyl ester

: 1591-31-7
4-iodo-biphenyl

: 2369-31-5
1‐{[1,1'‐biphenyl]‐4‐yl}‐2,2,2‐trifluoroethanone

: 438495-27-3
1-([1,1’-biphenyl]-4-yl)-2,2,2-trifluoroethanol

Guidance literature:: 4-iodo-biphenyl; With TurboGrignard; toluene; In tetrahydrofuran; at -40 - 0 ℃; for 0.416667h; Inert atmosphere;

trifluoroacetic acid-methyl ester; In tetrahydrofuran; toluene; at -40 ℃; Inert atmosphere;
DOI:10.1002/ejoc.202000550

Reference yield:

: 2714-87-6
[1,1′-biphenyl]-4-carbonyl fluoride

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 2369-31-5
1‐{[1,1'‐biphenyl]‐4‐yl}‐2,2,2‐trifluoroethanone

: 2-([1,1’-biphenyl]-4-yl)-1,1,1,3,3,3-hexafluoropropan-2-yl [1,1’-biphenyl]-4-carboxylate

Guidance literature:: With potassium fluoride; Trimethyl borate; In 1,4-dioxane; at 80 ℃; for 2h; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.organomet.9b00849

Reference yield:

: 92-66-0
4-bromo-1,1'-biphenyl

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 2950-30-3
2-([1,1’-biphenyl]-4-yl)-1,1,1,3,3,3-hexafluoropropan-2-ol

: 2369-31-5
1‐{[1,1'‐biphenyl]‐4‐yl}‐2,2,2‐trifluoroethanone

: 2-([1,1’-biphenyl]-4-yl)-1,1,1,3,3,3-hexafluoropropan-2-yl [1,1’-biphenyl]-4-carboxylate

Guidance literature:: With potassium fluoride; Trimethyl borate; triethylamine; In 1,4-dioxane; at 80 ℃; for 16h; Inert atmosphere; Glovebox;
DOI:10.1021/acs.organomet.9b00849