[3-(METHOXYMETHOXY)PHENYL][4-(METHOXYMETHOXY)PHENYL]METHANONE

Base Information

• Chemical Name: [3-(METHOXYMETHOXY)PHENYL][4-(METHOXYMETHOXY)PHENYL]METHANONE
• CAS No.: 263395-66-0
• Molecular Formula: C₁₇H₁₈O₅
• Molecular Weight: 302.327
• Hs Code.: 2914509090
• Mol file: 263395-66-0.mol

Synonyms:[3-(METHOXYMETHOXY)PHENYL][4-(METHOXYMETHOXY)PHENYL]METHANONE;[3-(methoxymethoxy)phenyl][4-(methoxymethoxy)phenyl]methanone(SALTDATA: FREE)

Chemical Property of [3-(METHOXYMETHOXY)PHENYL][4-(METHOXYMETHOXY)PHENYL]METHANONE

Chemical Property:

• Vapor Pressure: 4.39E-08mmHg at 25°C
• Boiling Point: 444.1°C at 760 mmHg
• Flash Point: 196.2°C
• PSA: 53.99000
• Density: 1.157g/cm³
• LogP: 2.88300

Purity/Quality:

98% ^*data from raw suppliers

[3-(methoxymethoxy)phenyl][4-(methoxymethoxy)phenyl]methanone 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [3-(METHOXYMETHOXY)PHENYL][4-(METHOXYMETHOXY)PHENYL]METHANONE

There total 2 articles about [3-(METHOXYMETHOXY)PHENYL][4-(METHOXYMETHOXY)PHENYL]METHANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

(3-hydroxyphenyl)(4-hydroxyphenyl)methanone (611-81-4) + chloromethyl methyl ether (107-30-2) → 3-hydroxy-4'-(methoxymethoxy)benzophenone (263395-55-7) + (4-methoxymethoxy-phenyl)-(3-methoxymethoxy-phenyl)-methanone (263395-66-0)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 0 - 20 ℃; for 4h;

DOI:10.1016/S0040-4020(99)01061-3

Reference yield:

4,3'-dimethoxybenzophenone (75731-44-1) → (4-methoxymethoxy-phenyl)-(3-methoxymethoxy-phenyl)-methanone (263395-66-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / pyridine hydrochloride / 0.5 h / Heating

2: 31 percent / DIPEA / tetrahydrofuran / 4 h / 0 - 20 °C

With pyridine hydrochloride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; 1: Substitution / 2: Substitution;

DOI:10.1016/S0040-4020(99)01061-3

upstream raw materials:

(3-hydroxyphenyl)(4-hydroxyphenyl)methanone

chloromethyl methyl ether

4,3'-dimethoxybenzophenone