4,3'-Dimethoxybenzophenone

Base Information

• Chemical Name: 4,3'-Dimethoxybenzophenone
• CAS No.: 75731-44-1
• Molecular Formula: C15H14O3
• Molecular Weight: 242.274
• Hs Code.: 2914509090
• DSSTox Substance ID: DTXSID70447741
• Nikkaji Number: J641.234C
• Wikidata: Q82266625
• Mol file: 75731-44-1.mol

Synonyms:4,3'-DIMETHOXYBENZOPHENONE;75731-44-1;3,4'-dimethoxybenzophenone;(3-methoxyphenyl)-(4-methoxyphenyl)methanone;MFCD01311540;SCHEMBL2303699;DTXSID70447741;AKOS009347681;(3-METHOXYPHENYL)(4-METHOXYPHENYL)METHANONE

Chemical Property of 4,3'-Dimethoxybenzophenone

Chemical Property:

• Vapor Pressure: 1.94E-06mmHg at 25°C
• Boiling Point: 394.7oC at 760 mmHg
• Flash Point: 184.1oC
• PSA: 35.53000
• Density: 1.123g/cm3
• LogP: 2.93480
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 242.094294304
• Heavy Atom Count: 18
• Complexity: 269

Purity/Quality:

99% ^*data from raw suppliers

4,3'-Dimethoxybenzophenone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C(=O)C2=CC(=CC=C2)OC

Technology Process of 4,3'-Dimethoxybenzophenone

There total 24 articles about 4,3'-Dimethoxybenzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3-methoxyphenylboronic acid (10365-98-7,1107579-37-2) + 1-(4-methoxybenzoyl)piperidine-2,6-dione → 4,3'-dimethoxybenzophenone (75731-44-1)

Guidance literature:

With boric acid; palladium diacetate; potassium carbonate; tricyclohexylphosphine tetrafluoroborate; In tetrahydrofuran; at 65 ℃; for 15h; Inert atmosphere;

DOI:10.1039/c6ob00084c

Reference yield: 93.0%

m-anisoyl chloride (1711-05-3) + methoxybenzene (100-66-3) → 4,3'-dimethoxybenzophenone (75731-44-1)

Guidance literature:

With aluminum (III) chloride; In dichloromethane; at 0 - 5 ℃;

DOI:10.1016/j.cclet.2011.09.014

Reference yield: 86.0%

m-anisoyl chloride (1711-05-3) + tris(4-methoxyphenyl)bismuth (33397-21-6) → 4,3'-dimethoxybenzophenone (75731-44-1)

Guidance literature:

With triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; at 80 ℃; for 3h;

DOI:10.1016/j.tet.2007.10.047

upstream raw materials:

m-anisoyl chloride

methoxybenzene

3-Methoxybenzoic acid

3-hydroxy-4'-methoxybenzophenone

Downstream raw materials:

1-methoxy-3-(1-(4-methoxyphenyl)vinyl)benzene

(3-hydroxyphenyl)(4-hydroxyphenyl)methanone

(4-Dimethylamino-phenyl)-(4-methoxy-phenyl)-(3-methoxy-phenyl)-methanol

3-Methoxybenzoic acid