(9H-Fluoren-9-YL)methanamine hydrochloride

Base Information

• Chemical Name: (9H-Fluoren-9-YL)methanamine hydrochloride
• CAS No.: 34221-61-9
• Molecular Formula: C₁₄H₁₃N*ClH
• Molecular Weight: 231.725
• Hs Code.: 2921499090
• European Community (EC) Number: 808-676-6
• Mol file: 34221-61-9.mol

Synonyms:34221-61-9;(9H-FLUOREN-9-YL)METHANAMINE HYDROCHLORIDE;FLUOREN-9-YL-METHYLAMINE HYDROCHLORIDE;9H-fluoren-9-ylmethanamine;hydrochloride;1-(9H-FLUOREN-9-YL)METHANAMINE HYDROCHLORIDE;SCHEMBL3895426;MFCD06804511;BS-42574;CS-0186095;D97564;(9H-FLUOREN-9-YL)METHANAMINEHYDROCHLORIDE;A934395;Fluoren-9-yl-methylamine hydrochloride, AldrichCPR

Chemical Property of (9H-Fluoren-9-YL)methanamine hydrochloride

Chemical Property:

• Melting Point: 294 °C (decomp)
• PSA: 26.02000
• LogP: 4.25990
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 231.0814771
• Heavy Atom Count: 16
• Complexity: 203

Purity/Quality:

98%min ^*data from raw suppliers

Fluoren-9-yl-methylamineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)CN.Cl

Technology Process of (9H-Fluoren-9-YL)methanamine hydrochloride

There total 1 articles about (9H-Fluoren-9-YL)methanamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 9-aminomethylfluorene hydrochloride (34221-61-9)

Guidance literature:

Reference yield: 76.0%

Cyclohexyl isocyanide (931-53-3) + benzaldehyde (100-52-7) + N-(Benzyloxycarbonyl)glycine (1138-80-3) + 9-aminomethylfluorene hydrochloride (34221-61-9) → {[(Cyclohexylcarbamoyl-phenyl-methyl)-(9H-fluoren-9-ylmethyl)-carbamoyl]-methyl}-carbamic acid benzyl ester (79755-74-1)

Guidance literature:

With triethylamine; In methanol; for 16h; Ambient temperature;

DOI:10.1039/c39810000491

Reference yield:

9-aminomethylfluorene hydrochloride (34221-61-9) → 9-methylene-fluorene (4425-82-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 76 percent / NEt₃ / methanol / 16 h / Ambient temperature

2: 79 percent / DBU / pyridine / 6 h / Ambient temperature

With 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; In pyridine; methanol;

DOI:10.1039/c39810000491

Downstream raw materials:

{[(Cyclohexylcarbamoyl-phenyl-methyl)-(9H-fluoren-9-ylmethyl)-carbamoyl]-methyl}-carbamic acid benzyl ester

9-methylene-fluorene