2-Furancarboxylic acid glycidyl ester

Base Information

• Chemical Name: 2-Furancarboxylic acid glycidyl ester
• CAS No.: 705-08-8
• Molecular Formula: C₈H₈O₄
• Molecular Weight: 168.149
• Mol file: 705-08-8.mol

Synonyms:2-Furancarboxylic acid glycidyl ester

Chemical Property of 2-Furancarboxylic acid glycidyl ester

Chemical Property:

• Boiling Point: 141 - 142 °C (1 mmHg)
• PSA: 51.97000
• LogP: 0.83520

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Furancarboxylic acid glycidyl ester

There total 4 articles about 2-Furancarboxylic acid glycidyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-furoic acid methyl ester (611-13-2) + oxiranyl-methanol (556-52-5) → glycidyl 2-furancarboxylate (705-08-8)

Guidance literature:

With tridodecylmethylammonium chloride; In hexane; at 69 ℃; for 2h;

DOI:10.1021/acscatal.7b03303

Reference yield: 75.0%

2-(2-hydroxyacetyl)furan (17678-19-2) + epichlorohydrin (106-89-8,24969-06-0,13403-37-7) → glycidyl 2-furancarboxylate (705-08-8)

Guidance literature:

With 18-crown-6 ether; oxygen; potassium carbonate; In water; at 80 ℃; for 10h; under 760.051 Torr;

DOI:10.1002/anie.201207206

Reference yield:

2-furanoic acid (88-14-2) + epichlorohydrin (106-89-8,24969-06-0,13403-37-7) → glycidyl 2-furancarboxylate (705-08-8)

Guidance literature:

2-furanoic acid; With methanol; sodium methylate; for 0.5h;

epichlorohydrin; at 100 ℃;

DOI:10.1246/bcsj.80.1391

upstream raw materials:

2-furanoic acid

epichlorohydrin

2-(2-hydroxyacetyl)furan

2-furoic acid methyl ester

Refernces

• 1、 -. "METHOD FOR PRODUCING GLYCIDYL ESTER". Paragraph 0032; 0034-0038; 0040-0041. . Retrieved 2017/11/09.
• 2、 Yamada, Wataru,Kitaichi, Yasunori,Tanaka, Hirotaka,Kojima, Tomohide,Sato, Mitsuo,Ikeno, Taketo,Yamada, Tohru. "Enantioselective incorporation of carbon dioxide into epoxides catalyzed by optically active cobalt(II) complexes". experimental part. p. 1391 - 1401. Retrieved 2009/06/20.