(4R,6R)-6-HydroxyMethyl-2,2-diMethyl-1,3-dioxane-4-acetic Acid 1,1-DiMethylethyl Ester

Base Information

Chemical Name:(4R,6R)-6-HydroxyMethyl-2,2-diMethyl-1,3-dioxane-4-acetic Acid 1,1-DiMethylethyl Ester
CAS No.:407577-54-2
Molecular Formula:C₁₃H₂₄O₅
Molecular Weight:260.331
Hs Code.:
Mol file:407577-54-2.mol

Synonyms:(4R,6R)-6-HydroxyMethyl-2,2-diMethyl-1,3-dioxane-4-acetic Acid 1,1-DiMethylethyl Ester;2,4-Dideoxy-3,5-O-(1-Methylethylidene)-L-threo-Hexonic Acid 1,1-DiMethylethyl Ester

Suppliers and Price of (4R,6R)-6-HydroxyMethyl-2,2-diMethyl-1,3-dioxane-4-acetic Acid 1,1-DiMethylethyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(4R,6R)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-aceticAcid1,1-DimethylethylEster
100mg
$ 1350.00

Medical Isotopes, Inc.
(4R,6R)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-aceticAcid1,1-DimethylethylEster
10 mg
$ 650.00

American Custom Chemicals Corporation
(4R,6R)-6-HYDROXYMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETIC ACID-1,1-DIMETHYLETHYL ESTER 95.00%
5MG
$ 498.77

Total 1 raw suppliers

Chemical Property of (4R,6R)-6-HydroxyMethyl-2,2-diMethyl-1,3-dioxane-4-acetic Acid 1,1-DiMethylethyl Ester

Chemical Property:

PSA：64.99000
LogP:1.62070

Purity/Quality:: (4R,6R)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-aceticAcid1,1-DimethylethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (4R,6R)-6-HydroxyMethyl-2,2-diMethyl-1,3-dioxane-4-acetic Acid 1,1-DiMethylethyl Ester is a useful synthetic intermediate in the preparation of Rosuvastatin (R700500) and its derivatives. A useful synthetic intermediate in the preparation of Rosuvastatin (R700500) and its derivatives.

Technology Process of (4R,6R)-6-HydroxyMethyl-2,2-diMethyl-1,3-dioxane-4-acetic Acid 1,1-DiMethylethyl Ester

There total 43 articles about (4R,6R)-6-HydroxyMethyl-2,2-diMethyl-1,3-dioxane-4-acetic Acid 1,1-DiMethylethyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 151140-38-4
tert-butyl 2-((4R,6S)-6-((benzyloxy)methyl)-2,2-dimethyl-1,3-dioxane-4-yl)acetate

: 124655-09-0,407577-54-2
1,1-dimethylethyl (4R-cis)-6-hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetate

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; at 31 - 33 ℃; for 5h; under 7600 Torr;
DOI:10.1055/s-1995-4028

Reference yield: 99.0%

: 154026-95-6
(4R-cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester

: 124655-09-0,407577-54-2
1,1-dimethylethyl (4R-cis)-6-hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetate

Guidance literature:: With methanol; In methylamine; at 60 - 70 ℃;

Reference yield: 94.0%

: (4R,6S)-6-[t-butoxycarbonylmethyl]-2,2-dimethyl-1,3-dioxane-4-carboxylic acid

: 124655-09-0,407577-54-2
1,1-dimethylethyl (4R-cis)-6-hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetate

Guidance literature:: With borane; sodium hydrogencarbonate; In tetrahydrofuran; at 20 ℃; for 1.5h; pH=8; pH-value; Reagent/catalyst; Inert atmosphere;