2-Piperazin-1-yl-quinazoline

Base Information

Chemical Name:2-Piperazin-1-yl-quinazoline
CAS No.:51047-61-1
Molecular Formula:12H14N4
Molecular Weight:214.27
Hs Code.:
DSSTox Substance ID:DTXSID201308966
Mol file:51047-61-1.mol

Synonyms:2-Piperazin-1-yl-quinazoline;2-piperazin-1-ylquinazoline;51047-61-1;2-Piperazinylquinazoline;1-Quinazolin-2-ylpiperazine;2-(1-Piperazinyl)quinazoline;piperazinyl quinazoline;SCHEMBL1029333;2-(piperazin-1-yl)-quinazoline;DTXSID201308966;FT-0717175

Suppliers and Price of 2-Piperazin-1-yl-quinazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
2-(1-piperazinyl)-Quinazoline 97.00%
25G
$ 5120.00

AccelPharmtech
2-(1-piperazinyl)-Quinazoline 97.00%
5G
$ 2750.00

AccelPharmtech
2-(1-piperazinyl)-Quinazoline 97.00%
1G
$ 2370.00

Total 2 raw suppliers

Chemical Property of 2-Piperazin-1-yl-quinazoline

Chemical Property:

Boiling Point:416.5±55.0 °C(Predicted)
PKA:8.68±0.10(Predicted)
PSA：41.05000
Density:1.201
LogP:1.43320
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:214.121846464
Heavy Atom Count:16
Complexity:227

Purity/Quality:

99% ^*data from raw suppliers

2-(1-piperazinyl)-Quinazoline 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)C2=NC3=CC=CC=C3C=N2

Technology Process of 2-Piperazin-1-yl-quinazoline

There total 1 articles about 2-Piperazin-1-yl-quinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 110-85-0
piperazine

: 6141-13-5
2-chloroquinazoline

: 51047-61-1
1-quinazolin-2-ylpiperazine

Guidance literature:: In toluene;

Reference yield: 87.0%

: 51047-61-1
1-quinazolin-2-ylpiperazine

: 622-95-7
4-chlorobenzyl bromide

: 1-(quinazolin-2-yl)-4-(1-[4-chlorophenyl]methyl)-piperazine hydrochloride

Guidance literature:: 1-quinazolin-2-ylpiperazine; 4-chlorobenzyl bromide; With potassium carbonate; In acetonitrile; at 60 ℃; for 4h;

With hydrogenchloride; In diethyl ether; water; acetonitrile;