2-(3-Chloropyridin-2-yl)sulfanyl-1-phenylethanone

Base Information

Chemical Name:2-(3-Chloropyridin-2-yl)sulfanyl-1-phenylethanone
CAS No.:5898-34-0
Molecular Formula:C18H18Cl2N4O2
Molecular Weight:263.7426
Hs Code.:
NSC Number:98859
DSSTox Substance ID:DTXSID60974475
Wikidata:Q82958810

Synonyms:5898-34-0;NSC98859;NCIOpen2_006682;DTXSID60974475;NSC-98859;2-[(3-Chloropyridin-2-yl)sulfanyl]-1-phenylethan-1-one

Suppliers and Price of 2-(3-Chloropyridin-2-yl)sulfanyl-1-phenylethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-(3-Chloropyridin-2-yl)sulfanyl-1-phenylethanone

Chemical Property:

Vapor Pressure:1.48E-12mmHg at 25°C
Boiling Point:396.6°Cat760mmHg
Flash Point:193.7°C
Density:1.32g/cm³
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:263.0171628
Heavy Atom Count:17
Complexity:256

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)CSC2=C(C=CC=N2)Cl

Technology Process of 2-(3-Chloropyridin-2-yl)sulfanyl-1-phenylethanone

There total 3 articles about 2-(3-Chloropyridin-2-yl)sulfanyl-1-phenylethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5897-94-9
3-Chloro-2-mercapto-pyridine

: 70-11-1
α-bromoacetophenone

: 5898-34-0
2-(3-chloro-pyridin-2-ylsulfanyl)-1-phenyl-ethanone

Guidance literature:: 3-Chloro-2-mercapto-pyridine; With sodium carbonate; In ethanol; water; at 20 ℃; for 0.5h;

α-bromoacetophenone; In ethanol; water; at 20 ℃; for 3h;
DOI:10.1021/acs.orglett.0c03521

Reference yield:

: 2402-77-9
2,3-dichloro-pyridine

: 5898-34-0
2-(3-chloro-pyridin-2-ylsulfanyl)-1-phenyl-ethanone

Guidance literature:: Multi-step reaction with 2 steps

1.1: thiourea / ethanol / 48 h / 85 °C

1.2: 2 h / 95 °C

2.1: sodium carbonate / ethanol; water / 0.5 h / 20 °C

2.2: 3 h / 20 °C

With sodium carbonate; thiourea; In ethanol; water;
DOI:10.1021/acs.orglett.0c03521