tert-butyl 4-(2-methoxy-5-nitrophenyl)piperazine-1-carboxylate

Base Information

Chemical Name:tert-butyl 4-(2-methoxy-5-nitrophenyl)piperazine-1-carboxylate
CAS No.:177488-99-2
Molecular Formula:C15H23N3O3
Molecular Weight:337.376
Hs Code.:

Synonyms:1-(tert-Butyl)-4-(2-Methoxy-5-nitrophenyl)piperazine;tert-Butyl 4-(2-Methoxy-5-nitrophenyl)piperazine-

Suppliers and Price of tert-butyl 4-(2-methoxy-5-nitrophenyl)piperazine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of tert-butyl 4-(2-methoxy-5-nitrophenyl)piperazine-1-carboxylate

Chemical Property:

Vapor Pressure:1.08E-09mmHg at 25°C
Boiling Point:488.5°C at 760 mmHg
Flash Point:249.3°C
Density:1.223g/cm³

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl 4-(2-methoxy-5-nitrophenyl)piperazine-1-carboxylate

There total 1 articles about tert-butyl 4-(2-methoxy-5-nitrophenyl)piperazine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 58315-37-0
1-(2-methoxy-5-nitrophenyl)piperazine

: 177488-99-2
tert-butyl 4-(2-methoxy-5-nitrophenyl)piperazine-1-carboxylate

Guidance literature:: With potassium carbonate; In tetrahydrofuran; water; for 18h; Ambient temperature;
DOI:10.1021/jm980532e

Reference yield: 99.0%

: 177488-99-2
tert-butyl 4-(2-methoxy-5-nitrophenyl)piperazine-1-carboxylate

: 148546-91-2
tert-butyl 4-(5-amino-2-methoxyphenyl)piperazine-1-carboxylate

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; for 18h; Ambient temperature;
DOI:10.1021/jm980532e

Reference yield:

: 177488-99-2
tert-butyl 4-(2-methoxy-5-nitrophenyl)piperazine-1-carboxylate

: 209481-82-3
tert-butyl 4-(5-{[(5-chloro-3-methyl-1-benzothien-2-yl)sulfonyl]amino}-2-methoxyphenyl)piperazine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / H₂ / 10 percent Pd/C / ethanol / 18 h / Ambient temperature

2: 97 percent / pyridine / CH₂Cl₂ / 18 h / Ambient temperature

With pyridine; hydrogen; palladium on activated charcoal; In ethanol; dichloromethane;
DOI:10.1021/jm980532e