N-(4-Biphenylyl)phthalic acid imide

Base Information

• Chemical Name: N-(4-Biphenylyl)phthalic acid imide
• CAS No.: 1592-49-0
• Molecular Formula: C20H13 N O2
• Molecular Weight: 299.329
• Hs Code.: 2925190090
• Mol file: 1592-49-0.mol

Synonyms:Phthalimide,N-4-biphenylyl- (7CI,8CI); N-p-Biphenylylphthalimide; NSC 243500

Chemical Property of N-(4-Biphenylyl)phthalic acid imide

Chemical Property:

• Vapor Pressure: 2.07E-10mmHg at 25°C
• Melting Point: 288 °C
• Boiling Point: 507.2°C at 760 mmHg
• PKA: -0.67±0.20(Predicted)
• Flash Point: 238.3°C
• PSA: 37.38000
• Density: 1.289g/cm³
• LogP: 4.21920

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(4-Biphenylyl)phthalic acid imide

There total 4 articles about N-(4-Biphenylyl)phthalic acid imide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

1,2-Diiodobenzene (615-42-9) + carbon monoxide (201230-82-2) + 4-phenylalanine (92-67-1) → 2-([1,1'-biphenyl]-4-yl)isoindoline-1,3-dione (1592-49-0)

Guidance literature:

With bis(triphenylphosphine)palladium(II)-chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; In N,N-dimethyl acetamide; at 115 ℃; for 3.6h; under 4654.3 - 4912.9 Torr;

DOI:10.1021/jo00023a023

Reference yield: 40.0%

N-hydroxyphthalimide (524-38-9) + 4-phenylalanine (92-67-1) → 2-([1,1'-biphenyl]-4-yl)isoindoline-1,3-dione (1592-49-0)

Guidance literature:

In aq. phosphate buffer; at 20 ℃; for 24h; pH=7;

DOI:10.1039/c4cc08503e

Reference yield:

phthalic anhydride (85-44-9) + 4-phenylalanine (92-67-1) → 2-([1,1'-biphenyl]-4-yl)isoindoline-1,3-dione (1592-49-0)

Guidance literature:

at 160 ℃;

upstream raw materials:

phthalic anhydride

4-phenylalanine

1,2-Diiodobenzene

carbon monoxide