4-chlorobenzenepentanol

Base Information

• Chemical Name: 4-chlorobenzenepentanol
• CAS No.: 14469-86-4
• Molecular Formula: C₁₁H₁₅ClO
• Molecular Weight: 198.692
• Mol file: 14469-86-4.mol

Synonyms:4-chlorobenzenepentanol

Chemical Property of 4-chlorobenzenepentanol

Chemical Property:

• PSA: 20.23000
• LogP: 3.04510

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-chlorobenzenepentanol

There total 4 articles about 4-chlorobenzenepentanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-(4-chlorophenyl)pentanoic acid (161725-12-8) → 1-Hydroxy-5-<4-chlor-phenyl>-pentan (14469-86-4)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at -20 - 20 ℃; for 4h;

DOI:10.1111/bph.14874

Reference yield:

4-chlorobenzaldehyde (104-88-1) → 1-Hydroxy-5-<4-chlor-phenyl>-pentan (14469-86-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / 0 °C

1.2: 4 h / 0 - 20 °C

2.1: hydrogen / benzene / 20 °C

3.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / -20 - 20 °C

With lithium aluminium tetrahydride; potassium tert-butylate; hydrogen; In tetrahydrofuran; benzene;

DOI:10.1111/bph.14874

Reference yield:

(E)-1-chloro-4-(pent-1-en-1-yl)benzene (18654-74-5) → 1-Hydroxy-5-<4-chlor-phenyl>-pentan (14469-86-4)

Guidance literature:

Multistep reaction; (i) B₂H₆, (ii) (heating), (iii) aq. H₂O₂, aq. NaOH;

DOI:10.1039/j39670000235

upstream raw materials:

(E)-1-chloro-4-(pent-1-en-1-yl)benzene

4-chlorobenzaldehyde

5-(4-chlorophenyl)pentanoic acid

Downstream raw materials:

5-(4-chlorophenyl)-pentyl bromide

1,12-Bis-<4-chlor-phenyl>-dodecen-(6)

1,12-Bis-(4-chlorphenyl)-dodecin-⁽⁶⁾