benzyl 3-(((Methylsulfonyl)oxy)Methyl)pyrrolidine-1-carboxylate

Base Information

• Chemical Name: benzyl 3-(((Methylsulfonyl)oxy)Methyl)pyrrolidine-1-carboxylate
• CAS No.: 1355455-26-3
• Molecular Formula: C14H19NO5S
• Molecular Weight: 313.375
• Mol file: 1355455-26-3.mol

Synonyms:benzyl 3-(((Methylsulfonyl)oxy)Methyl)pyrrolidine-1-carboxylate

Chemical Property of benzyl 3-(((Methylsulfonyl)oxy)Methyl)pyrrolidine-1-carboxylate

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of benzyl 3-(((Methylsulfonyl)oxy)Methyl)pyrrolidine-1-carboxylate

There total 3 articles about benzyl 3-(((Methylsulfonyl)oxy)Methyl)pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanesulfonyl chloride (124-63-0) + benzyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate (315718-05-9) → benzyl 3-{[(methylsulfonyl)oxy]methyl}pyrrolidine-1-carboxylate (1355455-26-3)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃;

DOI:10.1055/s-0030-1260223

Reference yield:

pyrrolidin-3-ylmethanol (85310-69-6,110013-18-8,110013-19-9,5082-74-6) → benzyl 3-{[(methylsulfonyl)oxy]methyl}pyrrolidine-1-carboxylate (1355455-26-3)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine

2: triethylamine / dichloromethane / 0 °C

With triethylamine; In dichloromethane;

DOI:10.1055/s-0030-1260223

Reference yield:

benzyl chloroformate (501-53-1,94274-21-2) → benzyl 3-{[(methylsulfonyl)oxy]methyl}pyrrolidine-1-carboxylate (1355455-26-3)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine

2: triethylamine / dichloromethane / 0 °C

With triethylamine; In dichloromethane;

DOI:10.1055/s-0030-1260223

upstream raw materials:

methanesulfonyl chloride

benzyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate

pyrrolidin-3-ylmethanol

benzyl chloroformate

Downstream raw materials:

benzyl 3-[(chlorosulfonyl)methyl]pyrrolidine-1-carboxylate

benzyl 3-[(acetylthio)methyl]pyrrolidine-1-carboxylate