(R)-3-METHOXY-PYRROLIDINE HYDROCHLORIDE

Base Information

• Chemical Name: (R)-3-METHOXY-PYRROLIDINE HYDROCHLORIDE
• CAS No.: 474707-30-7
• Molecular Formula: C5H11NO.ClH
• Molecular Weight: 137.609
• Hs Code.: 2933998090
• Mol file: 474707-30-7.mol

Synonyms:(3R)-3-METHOXYPYRROLIDINE HYDROCHLORIDE;(R)-3-METHOXY-PYRROLIDINE HYDROCHLORIDE;(R)-3-Methoxypyrrolidine HCl

Chemical Property of (R)-3-METHOXY-PYRROLIDINE HYDROCHLORIDE

Chemical Property:

• PSA: 21.26000
• LogP: 1.12550
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

(R)-3-MethoxypyrrolidineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (R)-3-METHOXY-PYRROLIDINE HYDROCHLORIDE

There total 2 articles about (R)-3-METHOXY-PYRROLIDINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3R-methoxypyrrolidine-1-carboxylic acid tert-butyl ester (549532-08-3) → (3R)-3-methoxypyrrolidine hydrochloride (474707-30-7)

Guidance literature:

With hydrogenchloride; In dichloromethane; at 0 - 20 ℃; for 48h;

Reference yield:

→ (3R)-3-methoxypyrrolidine hydrochloride (474707-30-7)

Guidance literature:

Reference yield: 100.0%

(3R)-3-methoxypyrrolidine hydrochloride (474707-30-7) + m-iodonitrobenzene (645-00-1) → (R)-3-methoxy-1-(3-nitrophenyl)pyrrolidine

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; at 110 ℃; for 16h;

upstream raw materials:

3R-methoxypyrrolidine-1-carboxylic acid tert-butyl ester

Downstream raw materials:

(R)-3-methoxy-1-((S)-1-(trityloxy)propan-2-yl)pyrrolidine

2-[(3R)-3-methoxypyrrolidin-1-yl]ethanol