1-Azetidinecarboxylic acid, 3-(2H-tetrazol-5-yl)-, 1,1-diMethylethyl ester

Base Information

• Chemical Name: 1-Azetidinecarboxylic acid, 3-(2H-tetrazol-5-yl)-, 1,1-diMethylethyl ester
• CAS No.: 1009367-63-8
• Molecular Formula: C₉H₁₅N₅O₂
• Molecular Weight: 225.25
• Hs Code.: 2933990090
• Mol file: 1009367-63-8.mol

Synonyms:1-Azetidinecarboxylic acid, 3-(2H-tetrazol-5-yl)-, 1,1-diMethylethyl ester;tert-butyl 3-(2H-1,2,3,4-tetrazol-5-yl)azetidine-1-carboxylate;tert-Butyl 3-(2H-tetrazol-5-yl)azetidine-1-carboxylate

Chemical Property of 1-Azetidinecarboxylic acid, 3-(2H-tetrazol-5-yl)-, 1,1-diMethylethyl ester

Chemical Property:

• PSA: 84.00000
• LogP: 0.47190
• Storage Temp.: 2-8°C

Purity/Quality:

98.5% ^*data from raw suppliers

tert-Butyl3-(2H-Tetrazol-5-yl)azetidine-1-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Azetidinecarboxylic acid, 3-(2H-tetrazol-5-yl)-, 1,1-diMethylethyl ester

There total 3 articles about 1-Azetidinecarboxylic acid, 3-(2H-tetrazol-5-yl)-, 1,1-diMethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.6%

tert-butyl 3-cyanoazetidine-1-carboxylate (142253-54-1) → tert-butyl 3-(2H-tetrazol-5-yl)azetidine-1-carboxylate (1009367-63-8)

Guidance literature:

With azidotrimethyltin; In toluene; at 100 ℃; for 18h;

Reference yield: 56.0%

tert-butyl 3-cyanoazetidine-1-carboxylate (142253-54-1) → tert-Butyl 3-(1 H-tetrazol-5-yl)azetidine-1-carboxylate (1009367-63-8)

Guidance literature:

With azidotrimethyltin; In toluene; at 100 ℃;

Reference yield: 56.0%

azidotrimethyltin (1118-03-2) + tert-butyl 3-cyanoazetidine-1-carboxylate (142253-54-1) → tert-Butyl 3-(1 H-tetrazol-5-yl)azetidine-1-carboxylate (1009367-63-8)

Guidance literature:

In toluene; at 100 ℃;

upstream raw materials:

tert-butyl 3-cyanoazetidine-1-carboxylate

azidotrimethyltin

Refernces

• 1、 -. "NEW THIADIAZOLE DERIVATIVES". Page/Page column 49. . Retrieved 2011/04/24.