1-(4-O-Methoxymethyl-4-hydroxyphenyl)-4-(4-nitrophenyl)piperazine

Base Information

Chemical Name:1-(4-O-Methoxymethyl-4-hydroxyphenyl)-4-(4-nitrophenyl)piperazine
CAS No.:1246819-65-7
Molecular Formula:C18H21N3O4
Molecular Weight:343.382
Hs Code.:
Mol file:1246819-65-7.mol

Synonyms:1-(4-O-Methoxymethyl-4-hydroxyphenyl)-4-(4-nitrophenyl)piperazine

Suppliers and Price of 1-(4-O-Methoxymethyl-4-hydroxyphenyl)-4-(4-nitrophenyl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(4-O-METHOXYMETHYL-4-HYDROXYPHENYL)-4-(4-NITROPHENYL)PIPERAZINE 95.00%
5MG
$ 504.98

Total 3 raw suppliers

Chemical Property of 1-(4-O-Methoxymethyl-4-hydroxyphenyl)-4-(4-nitrophenyl)piperazine

Chemical Property:

PSA：70.76000
LogP:3.55730
Solubility.:Chloroform, Dichloromethane,

Purity/Quality:

95% ^*data from raw suppliers

1-(4-O-METHOXYMETHYL-4-HYDROXYPHENYL)-4-(4-NITROPHENYL)PIPERAZINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(4-O-Methoxymethyl-4-hydroxyphenyl)-4-(4-nitrophenyl)piperazine

There total 3 articles about 1-(4-O-Methoxymethyl-4-hydroxyphenyl)-4-(4-nitrophenyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 107-30-2
chloromethyl methyl ether

: 112559-81-6
N-(4-Hydroxyphenyl)-N'-(4'-nitrophenyl)-piperazine

: 1246819-65-7
1-(4-(methoxymethoxy)phenyl)-4-(4-nitrophenyl)piperazine

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 16h; Inert atmosphere;
DOI:10.1021/jm200944b

Reference yield:

: 100-00-5
4-chlorobenzonitrile

: 1246819-65-7
1-(4-(methoxymethoxy)phenyl)-4-(4-nitrophenyl)piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / 1-methyl-pyrrolidin-2-one / 125 °C / Inert atmosphere

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 16 h / 20 °C / Inert atmosphere

With N-ethyl-N,N-diisopropylamine; In 1-methyl-pyrrolidin-2-one; dichloromethane;
DOI:10.1021/jm200944b

Reference yield:

: 56621-48-8
1-(4-hydroxyphenyl)piperazine

: 1246819-65-7
1-(4-(methoxymethoxy)phenyl)-4-(4-nitrophenyl)piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / 1-methyl-pyrrolidin-2-one / 125 °C / Inert atmosphere

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 16 h / 20 °C / Inert atmosphere

With N-ethyl-N,N-diisopropylamine; In 1-methyl-pyrrolidin-2-one; dichloromethane;
DOI:10.1021/jm200944b