6-chloro-N-phenylpyrazin-2-amine

Base Information

Chemical Name:6-chloro-N-phenylpyrazin-2-amine
CAS No.:642459-03-8
Molecular Formula:C₁₀H₈ClN₃
Molecular Weight:205.647
Hs Code.:
DSSTox Substance ID:DTXSID201301053
ChEMBL ID:CHEMBL448853

Synonyms:6-chloro-N-phenylpyrazin-2-amine;642459-03-8;6-CHLORO-N-PHENYL-2-PYRAZINAMINE;6-(Chloropyrazin-2-yl)phenylamine;CHEMBL448853;SCHEMBL1678613;BDBM24630;IMACCNVRJOXLEO-UHFFFAOYSA-N;DTXSID201301053;6-chloro-N-phenylpyrazin-2-amine, 9;AKOS009154768;DS-15950;BB 0261934;CS-0326746;FT-0707026;D84288;A914951

Suppliers and Price of 6-chloro-N-phenylpyrazin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 7 raw suppliers

Chemical Property of 6-chloro-N-phenylpyrazin-2-amine

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:205.0406750
Heavy Atom Count:14
Complexity:171

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)NC2=CN=CC(=N2)Cl

Technology Process of 6-chloro-N-phenylpyrazin-2-amine

There total 1 articles about 6-chloro-N-phenylpyrazin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 4774-14-5
2,6-dichloropyrazine

: 62-53-3
aniline

: 642459-03-8
6-(chloropyrazin-2-yl)phenylamine

Guidance literature:: In N-methylpyrrolidine (NMP); at 190 ℃; for 0.333333h; under 760.051 Torr; Microwave;

Reference yield: 76.0%

: 642459-03-8
6-(chloropyrazin-2-yl)phenylamine

: 87199-15-3
[3-(hydroxymethyl)phenyl]boronic acid

: (3-(6-(phenylamino)pyrazin-2-yl)phenyl)methanol

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium carbonate; In 1,4-dioxane; water; at 100 ℃; Inert atmosphere;
DOI:10.1016/j.bmc.2014.02.024

Reference yield: 49.0%

: 642459-03-8
6-(chloropyrazin-2-yl)phenylamine

: 75-89-8
2,2,2-trifluoroethanol

: 642459-13-0
(6-methylsulfanyl-pyrazin-2-yl)-phenyl-amine

: 642459-12-9
phenyl-[6-(2,2,2-trifluoroethoxy)-pyrazin-2-yl]-amine

Guidance literature:: 2,2,2-trifluoroethanol; With sodium hydride; dimethyl sulfoxide; for 0.25h;

6-(chloropyrazin-2-yl)phenylamine; In dimethyl sulfoxide; at 80 ℃; for 72h;