2-BroMo-6-fluoro-3-nitrobenzoic acid

Base Information

• Chemical Name: 2-BroMo-6-fluoro-3-nitrobenzoic acid
• CAS No.: 1036388-81-4
• Molecular Formula: C7H3BrFNO4
• Molecular Weight: 264.008
• Hs Code.: 2916399090
• Mol file: 1036388-81-4.mol

Synonyms:2-BroMo-6-fluoro-3-nitrobenzoic acid;2-Bromo-3-carboxy-4-fluoronitrobenzene

Chemical Property of 2-BroMo-6-fluoro-3-nitrobenzoic acid

Chemical Property:

• Boiling Point: 331.0±42.0 °C(Predicted)
• PKA: 1.01±0.29(Predicted)
• PSA: 83.12000
• Density: 1.967±0.06 g/cm3(Predicted)
• LogP: 2.71780
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-6-fluoro-3-nitrobenzoic acid 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-BroMo-6-fluoro-3-nitrobenzoic acid

There total 2 articles about 2-BroMo-6-fluoro-3-nitrobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

2-bromo-6-fluorobenzoic acid (2252-37-1) → 2-bromo-6-fluoro-3-nitrobenzoic acid (1036388-81-4)

Guidance literature:

With sulfuric acid; nitric acid; In water; at 20 ℃; for 2h;

Reference yield:

2-bromo-6-fluorobenzoic acid (2252-37-1) → 6-bromo-2-fluoro-3-nitrobenzoic acid (1036388-83-6) + 2-bromo-6-fluoro-3-nitrobenzoic acid (1036388-81-4)

Guidance literature:

With sulfuric acid; nitric acid; at 0 - 20 ℃; for 2.16667h;

Reference yield: 96.0%

methanol (67-56-1) + 2-bromo-6-fluoro-3-nitrobenzoic acid (1036388-81-4) → 2-bromo-6-fluoro-3-nitrobenzoate methyl ester

Guidance literature:

2-bromo-6-fluoro-3-nitrobenzoic acid; With thionyl chloride; for 1h; Reflux;

methanol; In water; for 1h; Reflux;

upstream raw materials:

2-bromo-6-fluorobenzoic acid

Downstream raw materials:

3-amino-2-cyano-6-fluorobenzoate methyl ester

C₉H₇FN₂O₂