4-(4-Iodo-phenyl)-4-oxo-butyric acid

Base Information

Chemical Name:4-(4-Iodo-phenyl)-4-oxo-butyric acid
CAS No.:194146-02-6
Molecular Formula:C10H9IO3
Molecular Weight:304.084
Hs Code.:2918300090
DSSTox Substance ID:DTXSID10366402
Wikidata:Q82151602
Mol file:194146-02-6.mol

Synonyms:194146-02-6;4-(4-Iodo-phenyl)-4-oxo-butyric acid;4-(4-Iodophenyl)-4-oxobutyric acid;4-(4-iodophenyl)-4-oxobutanoic acid;MFCD02260894;Enamine_005281;C10H9IO3;DTXSID10366402;HMS1409A01;4-(4-Iodophenyl)-4-oxobutyricacid;AKOS000122587;CS-0219787;EN300-04939;SR-01000041079;J-012573;SR-01000041079-1;Z56899021

Suppliers and Price of 4-(4-Iodo-phenyl)-4-oxo-butyric acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Rieke Metals
4-(4-Iodophenyl)-4-oxobutyricacid 97%
1g
$ 303.00

Rieke Metals
4-(4-Iodophenyl)-4-oxobutyricacid 97%
2g
$ 529.00

Rieke Metals
4-(4-Iodophenyl)-4-oxobutyricacid 97%
5g
$ 1250.00

Matrix Scientific
4-(4-Iodophenyl)-4-oxobutyric acid
5g
$ 1165.00

Matrix Scientific
4-(4-Iodophenyl)-4-oxobutyric acid
2g
$ 525.00

Matrix Scientific
4-(4-Iodophenyl)-4-oxobutyric acid
1g
$ 319.00

Crysdot
4-(4-Iodophenyl)-4-oxobutyricacid 95+%
1g
$ 316.00

Crysdot
4-(4-Iodophenyl)-4-oxobutyricacid 95+%
5g
$ 1156.00

American Custom Chemicals Corporation
4-(4-IODO-PHENYL)-4-OXO-BUTYRIC ACID 95.00%
5G
$ 1421.65

American Custom Chemicals Corporation
4-(4-IODO-PHENYL)-4-OXO-BUTYRIC ACID 95.00%
2.5G
$ 1147.43

Total 4 raw suppliers

Chemical Property of 4-(4-Iodo-phenyl)-4-oxo-butyric acid

Chemical Property:

Vapor Pressure:1.27E-08mmHg at 25°C
Boiling Point:442.9°C at 760 mmHg
Flash Point:221.6°C
PSA：54.37000
Density:1.781g/cm³
LogP:2.33870
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:303.95964
Heavy Atom Count:14
Complexity:219

Purity/Quality:

98%+ ^*data from raw suppliers

4-(4-Iodophenyl)-4-oxobutyricacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)CCC(=O)O)I

Technology Process of 4-(4-Iodo-phenyl)-4-oxo-butyric acid

There total 4 articles about 4-(4-Iodo-phenyl)-4-oxo-butyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 6945-94-4
4-(4-amino-phenyl)-4-oxo-butyric acid

: 194146-02-6
4-(4-iodophenyl)-4-oxobutanoic acid

Guidance literature:: 4-(4-amino-phenyl)-4-oxo-butyric acid; With hydrogenchloride; sodium nitrite; In water; at 0 ℃;

With potassium iodide; In water; at 20 ℃;
DOI:10.1016/j.tetlet.2016.04.093

Reference yield:

: 108-30-5
succinic acid anhydride

: 591-50-4
iodobenzene

: 194146-02-6
4-(4-iodophenyl)-4-oxobutanoic acid

Guidance literature:: With carbon disulfide; aluminium trichloride;
DOI:10.1021/ja01258a054

Reference yield:

: 103-84-4
Acetanilid

: 194146-02-6
4-(4-iodophenyl)-4-oxobutanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: aluminum (III) chloride / 1,2-dichloro-ethane

2.1: hydrogenchloride / water / Heating

3.1: hydrogenchloride; sodium nitrite / water / 0 °C

3.2: 20 °C

With hydrogenchloride; aluminum (III) chloride; sodium nitrite; In water; 1,2-dichloro-ethane; 1.1: |Friedel-Crafts Acylation;
DOI:10.1016/j.tetlet.2016.04.093