2-O-Deacetylevonine

Base Information

• Chemical Name: 2-O-Deacetylevonine
• CAS No.: 36017-57-9
• Molecular Formula: C₃₄H₄₁NO₁₆
• Molecular Weight: 719.697
• Mol file: 36017-57-9.mol

Synonyms:2-O-Deacetylevonine

Chemical Property of 2-O-Deacetylevonine

Chemical Property:

• Melting Point: 135 °C
• PSA: 237.45000
• LogP: 0.10010

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-O-Deacetylevonine

There total 2 articles about 2-O-Deacetylevonine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sodium acetate (127-09-3) + ent-(111S,5R)-15,11-epoxy-11β,12β,14,16α,19β,114-hexahydroxy-5r,6t-dimethyl-(13βH,17βH)-2,8-dioxa-1(12,3)-eudesmana-4(3,2)-pyridina-cyclooctaphane-18,3,7-trione (33376-79-3,35721-64-3) → 2-(deacetyl)evonine (36017-57-9)

Guidance literature:

With acetic anhydride; at 45 ℃; for 12h;

DOI:10.1016/0040-4020(78)80097-0

Reference yield:

evonine (33458-64-9) → 2-(deacetyl)evonine (36017-57-9)

Guidance literature:

With aluminum oxide; In diethyl ether; for 48h;

DOI:10.1007/BF00905663

Reference yield:

benzoyl chloride (98-88-4) + 2-(deacetyl)evonine (36017-57-9) → ent-(111S,5R)-11β,16α,19β,114-tetraacetoxy-12β-benzoyloxy-15,11-epoxy-14-hydroxy-5r,6t-dimethyl-(13βH,17βH)-2,8-dioxa-1(12,3)-eudesmana-4(3,2)-pyridina-cyclooctaphane-18,3,7-trione (41928-79-4)

Guidance literature:

With pyridine; at 45 ℃; for 36h;

DOI:10.1016/0040-4020(78)80097-0

upstream raw materials:

sodium acetate

ent-(1¹¹S,5R)-1^5,11-epoxy-1¹β,1²β,1⁴,1⁶α,1⁹β,1¹⁴-hexahydroxy-5r,6t-dimethyl-(1³βH,1⁷βH)-2,8-dioxa-1(12,3)-eudesmana-4(3,2)-pyridina-cyclooctaphane-1⁸,3,7-trione

evonine

Downstream raw materials:

ent-(1¹¹S,5R)-1¹β,1⁶α,1⁹β,1¹⁴-tetraacetoxy-1²β-benzoyloxy-1^5,11-epoxy-1⁴-hydroxy-5r,6t-dimethyl-(1³βH,1⁷βH)-2,8-dioxa-1(12,3)-eudesmana-4(3,2)-pyridina-cyclooctaphane-1⁸,3,7-trione

Refernces

• 1、 Yamada,Shizuri,Hirata. "Isolation and structures of a new alkaloid alatamine and an insecticidal alkaloid wilfordine from Euonymus alatus forma striatus (Thunb.) Makino". . p. 1915 - 1920. Retrieved 2007/10/07.