6-chloro-3,4-dihydro-2h-pyrido[3,2-b][1,4]oxazine

Base Information

Chemical Name:6-chloro-3,4-dihydro-2h-pyrido[3,2-b][1,4]oxazine
CAS No.:1303587-97-4
Molecular Formula:C7H7ClN2O
Molecular Weight:171.586
Hs Code.:2934999090
Mol file:1303587-97-4.mol

Synonyms:6-chloro-3,4-dihydro-2h-pyrido[3,2-b][1,4]oxazine;2H-Pyrazino[2,3-b]-1,4-oxazine, 6- chloro-3,4-dihydro-

Suppliers and Price of 6-chloro-3,4-dihydro-2h-pyrido[3,2-b][1,4]oxazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 6-chloro-3,4-dihydro-2h-pyrido[3,2-b][1,4]oxazine

Chemical Property:

Boiling Point:315.5±42.0 °C(Predicted)
PKA:1.21±0.20(Predicted)
PSA：34.15000
Density:1.409±0.06 g/cm3(Predicted)
LogP:1.67730
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-chloro-3,4-dihydro-2h-pyrido[3,2-b][1,4]oxazine

There total 1 articles about 6-chloro-3,4-dihydro-2h-pyrido[3,2-b][1,4]oxazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 1303587-96-3
3-amino-5-chloropyrazin-2-ol

: 106-93-4
ethylene dibromide

: 1303587-97-4
6-chloro-3,4-dihydro-2H-pyrazino[2,3-b][1,4]oxazine

Guidance literature:: With potassium carbonate; In acetonitrile; Reflux;

Reference yield: 27.0%

: 1303587-97-4
6-chloro-3,4-dihydro-2H-pyrazino[2,3-b][1,4]oxazine

: 1423-26-3
(meta-(trifluoromethyl)phenyl)boronic acid

: 1303587-98-5
6-(3-(trifluoromethyl)phenyl)-3,4-dihydro-2H-pyrazino[2,3-b][1,4]oxazine

Guidance literature:: With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; water; at 100 ℃; Inert atmosphere;

Reference yield:

: 1303587-97-4
6-chloro-3,4-dihydro-2H-pyrazino[2,3-b][1,4]oxazine

: 1303586-08-4
N-(4-methylthiazol-2-yl)-6-(3-(trifluoromethyl)phenyl)-2H-pyrazino[2,3-b][1,4]oxazine-4(3H)-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane; water / 100 °C / Inert atmosphere

2.1: triethylamine / dichloromethane / 0.5 h / 20 °C

2.2: 20 °C

With potassium carbonate; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; dichloromethane; water;