tert-butyl 4-(2-(2-ethoxy-2-oxoethoxy)phenyl)piperazine-1-carboxylate

Base Information

Chemical Name:tert-butyl 4-(2-(2-ethoxy-2-oxoethoxy)phenyl)piperazine-1-carboxylate
CAS No.:1008509-21-4
Molecular Formula:C₁₉H₂₈N₂O₅
Molecular Weight:364.442
Hs Code.:
Mol file:1008509-21-4.mol

Synonyms:tert-butyl 4-(2-(2-ethoxy-2-oxoethoxy)phenyl)piperazine-1-carboxylate

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Chemical Property of tert-butyl 4-(2-(2-ethoxy-2-oxoethoxy)phenyl)piperazine-1-carboxylate

Chemical Property:

Purity/Quality:

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MSDS Files:: SDS file from LookChem

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Technology Process of tert-butyl 4-(2-(2-ethoxy-2-oxoethoxy)phenyl)piperazine-1-carboxylate

There total 1 articles about tert-butyl 4-(2-(2-ethoxy-2-oxoethoxy)phenyl)piperazine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 105-36-2
ethyl bromoacetate

: 313657-51-1
tert-butyl 4-(2-hydroxyphenyl)piperazine-1-carboxylate

: 1008509-21-4
tert-butyl 4-[2-ethoxycarbonylmethoxy-phenyl]piperazine-1-carboxylate

Guidance literature:: With caesium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 12h;

Reference yield: 28.0%

: 1008509-21-4
tert-butyl 4-[2-ethoxycarbonylmethoxy-phenyl]piperazine-1-carboxylate

: 129722-34-5
7-(4-bromobutoxy)-3,4-dihydro-2(1H)-quinolinone

: 1085927-34-9
Ethyl 2-(2-(4-(4-(2-oxo-1,2,3,4-tetrahydroquinolin-7-yloxy)butyl)piperazin-1-yl)phenoxy)acetate

Guidance literature:: tert-butyl 4-[2-ethoxycarbonylmethoxy-phenyl]piperazine-1-carboxylate; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 8h;

7-(4-bromobutoxy)-3,4-dihydro-2(1H)-quinolinone; With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 70 ℃; for 6h;

Reference yield:

: 1008509-21-4
tert-butyl 4-[2-ethoxycarbonylmethoxy-phenyl]piperazine-1-carboxylate

: 1000894-45-0
C₁₇H₂₄N₂O₅

Guidance literature:: tert-butyl 4-[2-ethoxycarbonylmethoxy-phenyl]piperazine-1-carboxylate; With lithium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 2h;

With hydrogenchloride; water; pH=4.5;