1-hydroxy-3-methoxy-1,2-dimethyl-9H-carbazol-4-one

Base Information

Chemical Name:1-hydroxy-3-methoxy-1,2-dimethyl-9H-carbazol-4-one
CAS No.:115920-44-0
Molecular Formula:C₁₅H₁₅NO₃
Molecular Weight:257.289
Hs Code.:
DSSTox Substance ID:DTXSID00921867
Nikkaji Number:J936.804C
Wikidata:Q82895007
Mol file:115920-44-0.mol

Synonyms:carbazomycin G

Suppliers and Price of 1-hydroxy-3-methoxy-1,2-dimethyl-9H-carbazol-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
CARBAZOMYCIN G 95.00%
5MG
$ 502.46

Total 2 raw suppliers

Chemical Property of 1-hydroxy-3-methoxy-1,2-dimethyl-9H-carbazol-4-one

Chemical Property:

Vapor Pressure:1.29E-11mmHg at 25°C
Boiling Point:519.4°Cat760mmHg
Flash Point:267.9°C
PSA：62.32000
Density:1.33g/cm³
LogP:2.49210
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:257.10519334
Heavy Atom Count:19
Complexity:445

Purity/Quality:

96% ^*data from raw suppliers

CARBAZOMYCIN G 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=O)C2=C(C1(C)O)NC3=CC=CC=C32)OC

Technology Process of 1-hydroxy-3-methoxy-1,2-dimethyl-9H-carbazol-4-one

There total 29 articles about 1-hydroxy-3-methoxy-1,2-dimethyl-9H-carbazol-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 917-54-4
methyllithium

: 192188-88-8
3-methoxy-2-methyl-4,9-dihydro-1H-carbazole-1,4-dione

: 115920-44-0
carbazomycin G

Guidance literature:: In diethyl ether; at -78 - 20 ℃;
DOI:10.1016/S0040-4020(00)00543-3

Reference yield: 25.0%

: 676-58-4
methylmagnesium chloride

: 192188-88-8
3-methoxy-2-methyl-4,9-dihydro-1H-carbazole-1,4-dione

: 115920-44-0
carbazomycin G

: 543683-63-2
2,3-dimethyl-9H-carbazole-1,4-quinone

Guidance literature:: In tetrahydrofuran; at -78 ℃; for 2.5h;
DOI:10.1002/ejoc.200390116

Reference yield:

: 96502-90-8
acetic acid 2,4-dimethoxy-3-methyl-phenyl ester

: 115920-44-0
carbazomycin G

Guidance literature:: Multi-step reaction with 6 steps

1.1: 92 percent / HNO₃ / acetic acid; acetic anhydride / 0.75 h / 0 °C

2.1: 93 percent / KOH / ethanol; H₂O / 2 h / 20 °C

3.1: 95 percent / H₂ / Pd/C / methanol / 2.5 h / 20 °C / 800 - 900 Torr

4.1: acetonitrile / 48 h / 20 °C

4.2: Et₃N; DMAP / CH₂Cl₂ / 4 h / 20 °C

4.3: 188 mg / Alox B Super 1; MnO₂ / CH₂Cl₂ / 2 h / 20 °C

5.1: 95 percent / (NH₄)2Ce(NO₃)6 / acetonitrile; H₂O / 2 h / 0 °C

6.1: 30 percent / tetrahydrofuran / 2.5 h / -78 °C

With potassium hydroxide; ammonium cerium(IV) nitrate; hydrogen; nitric acid; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; water; acetic anhydride; acetic acid; acetonitrile;
DOI:10.1002/ejoc.200390116