2-Chloro-1-(3-methylindolin-1-yl)ethanone

Base Information

Chemical Name:2-Chloro-1-(3-methylindolin-1-yl)ethanone
CAS No.:66624-44-0
Molecular Formula:C11H12ClNO
Molecular Weight:209.67208
Hs Code.:2933990090
DSSTox Substance ID:DTXSID90496872

Synonyms:66624-44-0;2-Chloro-1-(3-methylindolin-1-yl)ethanone;SCHEMBL7550236;DTXSID90496872;ZJUJMJSVFDKIML-UHFFFAOYSA-N;2-Chloro-1-(3-methylindolinyl)ethan-1-one;2-Chloro-1-(3-methyl-2,3-dihydro-1H-indol-1-yl)ethan-1-one

Suppliers and Price of 2-Chloro-1-(3-methylindolin-1-yl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(CHLOROACETYL)-2,3-DIHYDRO-3-METHYL-1H-INDOLE 95.00%
5MG
$ 495.76

Total 4 raw suppliers

Chemical Property of 2-Chloro-1-(3-methylindolin-1-yl)ethanone

Chemical Property:

PSA：20.31000
LogP:2.44050
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:209.0607417
Heavy Atom Count:14
Complexity:231

Purity/Quality:

99% ^*data from raw suppliers

1-(CHLOROACETYL)-2,3-DIHYDRO-3-METHYL-1H-INDOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CN(C2=CC=CC=C12)C(=O)CCl

Technology Process of 2-Chloro-1-(3-methylindolin-1-yl)ethanone

There total 2 articles about 2-Chloro-1-(3-methylindolin-1-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 4375-15-9
3-methyl-2,3-dihydro-1H-indole

: 79-04-9
chloroacetyl chloride

: 66624-44-0
1-chloroacetyl-3-methyl-2,3-dihydro-indole

Guidance literature:: With triethylamine; In chloroform; at 0 ℃; for 2h;

Reference yield:

: 83-34-1
3-Methylindole

: 66624-44-0
1-chloroacetyl-3-methyl-2,3-dihydro-indole

Guidance literature:: Multi-step reaction with 2 steps

1: Me₃N-BH₃

2: TEA / CHCl₃ / 18 h / 20 °C

With trimethylamine-borane; TEA; In chloroform;
DOI:10.1016/S0960-894X(02)00655-8