5-[Bis(2-chloroethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid Methyl Ester

Base Information

Chemical Name:5-[Bis(2-chloroethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid Methyl Ester
CAS No.:109882-25-9
Molecular Formula:C17H23Cl2N3O2
Molecular Weight:372.295
Hs Code.:
Mol file:109882-25-9.mol

Synonyms:5-[Bis(2-chloroethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid Methyl Ester

Suppliers and Price of 5-[Bis(2-chloroethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid Methyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoicAcidMethylEster
100mg
$ 1320.00

American Custom Chemicals Corporation
5-[BIS-(2-CHLOROETHYL)AMINO]-1-METHYL-1H-BENZIMIDAZOLE-2-BUTANOIC ACID METHYL ESTER 95.00%
5MG
$ 504.34

Total 7 raw suppliers

Chemical Property of 5-[Bis(2-chloroethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid Methyl Ester

Chemical Property:

Melting Point:60-63 °C (decomp)
Boiling Point:536.4±50.0 °C(Predicted)
PKA:7.08±0.10(Predicted)
PSA：47.36000
Density:1.25±0.1 g/cm3(Predicted)
LogP:3.35300

Purity/Quality:

99% ^*data from raw suppliers

5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoicAcidMethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Impurity of Bendamustine (B132500), an anticancer drug.

Technology Process of 5-[Bis(2-chloroethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid Methyl Ester

There total 12 articles about 5-[Bis(2-chloroethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid Methyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1221157-11-4
4-(5-amino-1-methyl-1H-benzoimidazol-2-yl)butyric acid methyl ester hydrochloride

: 79-11-8
chloroacetic acid

: 109882-25-9
4-{5-[bis-(2-chloro-ethyl)amino]-1-methyl-1H-benzoimidazol-2-yl}butyric acid methyl ester

Guidance literature:: 4-(5-amino-1-methyl-1H-benzoimidazol-2-yl)butyric acid methyl ester hydrochloride; chloroacetic acid; In tetrahydrofuran; Inert atmosphere; Heating;

With borane-THF; In tetrahydrofuran; at 20 ℃;

With methanol; In tetrahydrofuran; at 20 ℃;