3-Chloro-4'-pyrrolidinomethyl benzophenone

Base Information

Chemical Name:3-Chloro-4'-pyrrolidinomethyl benzophenone
CAS No.:898776-32-4
Molecular Formula:C18H18ClNO
Molecular Weight:299.8
Hs Code.:2933990090
DSSTox Substance ID:DTXSID50582967
Wikidata:Q82474479
Mol file:898776-32-4.mol

Synonyms:3-chloro-4'-pyrrolidinomethyl benzophenone;898776-32-4;(3-chlorophenyl)-[4-(pyrrolidin-1-ylmethyl)phenyl]methanone;MFCD03841512;3-chloro-4'-pyrrolidinomethylbenzophenone;SCHEMBL2932980;DTXSID50582967;UVKZZQWHCZLWLJ-UHFFFAOYSA-N;AKOS016019747;(3-Chlorophenyl)[4-(pyrrolidin-1-ylmethyl)phenyl]methanone;(3-Chlorophenyl){4-[(pyrrolidin-1-yl)methyl]phenyl}methanone

Suppliers and Price of 3-Chloro-4'-pyrrolidinomethyl benzophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Rieke Metals
3-chloro-4'-pyrrolidinomethylbenzophenone 97%
1g
$ 467.00

Rieke Metals
3-chloro-4'-pyrrolidinomethylbenzophenone 97%
2g
$ 875.00

Rieke Metals
3-chloro-4'-pyrrolidinomethylbenzophenone 97%
5g
$ 1750.00

Matrix Scientific
3-Chloro-4'-pyrrolidinomethyl benzophenone 97%
5g
$ 1412.00

Matrix Scientific
3-Chloro-4'-pyrrolidinomethyl benzophenone 97%
2g
$ 726.00

Matrix Scientific
3-Chloro-4'-pyrrolidinomethyl benzophenone 97%
1g
$ 437.00

Crysdot
3-Chloro-4'-pyrrolidinomethylbenzophenone 95+%
1g
$ 433.00

Crysdot
3-Chloro-4'-pyrrolidinomethylbenzophenone 95+%
5g
$ 1401.00

American Custom Chemicals Corporation
3-CHLORO-4'-PYRROLIDINOMETHYL BENZOPHENONE 95.00%
10G
$ 3395.70

American Custom Chemicals Corporation
3-CHLORO-4'-PYRROLIDINOMETHYL BENZOPHENONE 95.00%
5G
$ 2243.59

Total 3 raw suppliers

Chemical Property of 3-Chloro-4'-pyrrolidinomethyl benzophenone

Chemical Property:

Vapor Pressure:1.15E-07mmHg at 25°C
Boiling Point:432°C at 760 mmHg
PKA:9.22±0.20(Predicted)
Flash Point:215.1°C
PSA：20.31000
Density:1.208g/cm³
LogP:4.10470
XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:299.1076919
Heavy Atom Count:21
Complexity:345

Purity/Quality:

97% ^*data from raw suppliers

3-chloro-4'-pyrrolidinomethylbenzophenone 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)CC2=CC=C(C=C2)C(=O)C3=CC(=CC=C3)Cl

Technology Process of 3-Chloro-4'-pyrrolidinomethyl benzophenone

There total 5 articles about 3-Chloro-4'-pyrrolidinomethyl benzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 123-75-1
pyrrolidine

: 945657-22-7
(4-bromomethyl-phenyl)(3-chloro-phenyl)methanone

: 898776-32-4
(3-chlorophenyl)[4-(pyrrolidin-1-ylmethyl)phenyl]methanone

Guidance literature:: With triethylamine; In acetonitrile; at 0 ℃; for 1h;
DOI:10.1016/j.bmcl.2007.04.077

Reference yield:

: 587-04-2
m-Chlorobenzaldehyde

: 898776-32-4
(3-chlorophenyl)[4-(pyrrolidin-1-ylmethyl)phenyl]methanone

Guidance literature:: Multi-step reaction with 2 steps

1.1: tetrahydrofuran / 6 h / Heating

1.2: N-bromosuccinimide; AIBN / CCl₄ / Heating

2.1: 78 percent / Et₃N / acetonitrile / 1 h / 0 °C

With triethylamine; In tetrahydrofuran; acetonitrile;
DOI:10.1016/j.bmcl.2007.04.077

Reference yield:

: 106-38-7
para-bromotoluene

: 898776-32-4
(3-chlorophenyl)[4-(pyrrolidin-1-ylmethyl)phenyl]methanone

Guidance literature:: Multi-step reaction with 3 steps

1.1: Mg; I₂ / tetrahydrofuran / Heating

1.2: 70 percent / tetrahydrofuran / 4 h / 75 °C

2.1: N-bromosuccinimide; α,α'-azobis(isobutyronitrile) / CCl4 / 3 h / Heating

3.1: 2.5 g / Et₃N / acetonitrile / 1 h / 0 °C

With N-Bromosuccinimide; azobisisobutyronitrile; iodine; magnesium; triethylamine; In tetrahydrofuran; tetrachloromethane; acetonitrile; 1.2: Grignard reaction;
DOI:10.1021/jm061429p