methyl 4-(3-chlorophenoxy)benzoate

Base Information

• Chemical Name: methyl 4-(3-chlorophenoxy)benzoate
• CAS No.: 1149-40-2
• Molecular Formula: C14H11ClO3
• Molecular Weight: 262.693
• Mol file: 1149-40-2.mol

Synonyms:methyl 4-(3-chlorophenoxy)benzoate

Chemical Property of methyl 4-(3-chlorophenoxy)benzoate

Chemical Property:

• PSA: 35.53000
• LogP: 3.91890

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 4-(3-chlorophenoxy)benzoate

There total 8 articles about methyl 4-(3-chlorophenoxy)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

3-monochlorophenol (108-43-0) + 4-methoxycarbonylphenylboronic acid (99768-12-4) → Methyl 4-(3-chlorophenoxy)benzoate (1149-40-2)

Guidance literature:

With pyridine; copper diacetate; In dichloromethane; at 20 ℃; for 48h; Molecular sieve;

DOI:10.1021/acs.jmedchem.0c02042

Reference yield:

3-chlorophenylboronic acid (63503-60-6) + methyl 4-hydroxylbenzoate (99-76-3,156291-94-0) → Methyl 4-(3-chlorophenoxy)benzoate (1149-40-2)

Guidance literature:

With pyridine; copper diacetate; In dichloromethane; for 2h; Molecular sieve;

DOI:10.1016/j.ejmech.2017.08.004

Reference yield:

para-bromoacetophenone (99-90-1) → Methyl 4-(3-chlorophenoxy)benzoate (1149-40-2)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) KOH, (ii) /BRN= 386015/

2: sodium hydroxide; potassium permanganate

3: hydrogenchloride

With hydrogenchloride; sodium hydroxide; potassium permanganate;

upstream raw materials:

methanol

4-(3-chlorophenoxy)benzoic acid

methyl 4-hydroxylbenzoate

1,3-Dichlorobenzene

Downstream raw materials:

4-<3-Chlor-4-butyryl-phenoxy>-benzoesaeure-methylester

4-<3-Chlor-4-butyryl-phenoxy>-benzoesaeure

4-<3-Chlor-4-(2-methylen-butyryl)-phenoxy>-benzoesaeure

4-(3-chlorophenoxy)benzoic acid