1,4-Piperidinedicarboxylic acid, 4-aMino-, 1-(1,1-diMethylethyl) 4-ethyl ester

Base Information

Chemical Name:1,4-Piperidinedicarboxylic acid, 4-aMino-, 1-(1,1-diMethylethyl) 4-ethyl ester
CAS No.:1187321-32-9
Molecular Formula:C₁₃H₂₄N₂O₄
Molecular Weight:272.345
Hs Code.:
Mol file:1187321-32-9.mol

Synonyms:1,4-Piperidinedicarboxylic acid, 4-aMino-, 1-(1,1-diMethylethyl) 4-ethyl ester;Ethyl 1-Boc-4-amino-piperidine-4-carboxylate;4-Amino-1-BOC-4-PiperidinediCarbocylic acid t-butyl ester

Suppliers and Price of 1,4-Piperidinedicarboxylic acid, 4-aMino-, 1-(1,1-diMethylethyl) 4-ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Amino-1-boc-4-piperidinedicarboxylicAcidEthylEster
100mg
$ 155.00

TRC
4-Amino-1-boc-4-piperidinedicarboxylicAcidEthylEster
10mg
$ 45.00

Crysdot
1-tert-Butyl4-ethyl4-aminopiperidine-1,4-dicarboxylate 95+%
1g
$ 465.00

Chemenu
1-tert-Butyl4-ethyl4-aminopiperidine-1,4-dicarboxylate 95%
1g
$ 439.00

Acrotein
Ethyl1-Boc-4-amino-piperidine-4-carboxylate 97%
1g
$ 302.50

Total 9 raw suppliers

Chemical Property of 1,4-Piperidinedicarboxylic acid, 4-aMino-, 1-(1,1-diMethylethyl) 4-ethyl ester

Chemical Property:

Boiling Point:349.2±42.0 °C(Predicted)
PKA:7.24±0.20(Predicted)
PSA：81.86000
Density:1.112±0.06 g/cm3(Predicted)
LogP:1.91610

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Amino-1-boc-4-piperidinedicarboxylicAcidEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1,4-Piperidinedicarboxylic acid, 4-aMino-, 1-(1,1-diMethylethyl) 4-ethyl ester

There total 2 articles about 1,4-Piperidinedicarboxylic acid, 4-aMino-, 1-(1,1-diMethylethyl) 4-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1187321-31-8
4-benzyloxycarbonylaminopiperidine-1,4-dicarboxylic acid-1-tert-butyl ester-4-ethyl ester

: 1187321-32-9
4-aminopiperidine-1,4-dicarboxylic acid-1-tert-butyl ester-4-ethyl ester

Guidance literature:: With hydrogen; 5%-palladium/activated carbon; In ethanol; for 2.25h;

Reference yield:

: 1093214-64-2
1-(tert-butoxycarbonyl)-4-(ethoxycarbonyl)piperidine-4-carboxylic acid

: 1187321-32-9
4-aminopiperidine-1,4-dicarboxylic acid-1-tert-butyl ester-4-ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: diphenyl phosphoryl azide; triethylamine / toluene / 0.75 h / 20 °C

1.2: 20 h / 80 °C

2.1: hydrogen / 5%-palladium/activated carbon / ethanol / 2.25 h

With diphenyl phosphoryl azide; hydrogen; triethylamine; 5%-palladium/activated carbon; In ethanol; toluene;

Reference yield:

: 1187321-32-9
4-aminopiperidine-1,4-dicarboxylic acid-1-tert-butyl ester-4-ethyl ester

: 203186-96-3
tert-butyl 4-amino-4-(hydroxymethyl)piperidine-1-carboxylate

Guidance literature:: 4-aminopiperidine-1,4-dicarboxylic acid-1-tert-butyl ester-4-ethyl ester; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 5 ℃; for 0.75h;

With ethyl acetate; In tetrahydrofuran; at 0 - 5 ℃; for 0.25h;