ethyl 3-{[(tert-butoxy)carbonyl]amino}propanoate

Base Information

• Chemical Name: ethyl 3-{[(tert-butoxy)carbonyl]amino}propanoate
• CAS No.: 88574-53-2
• Molecular Formula: C10H19NO4
• Molecular Weight: 217.265
• Mol file: 88574-53-2.mol

Synonyms:ethyl 3-{[(tert-butoxy)carbonyl]amino}propanoate;Ethyl 3-(Boc-amino)propanoate

Chemical Property of ethyl 3-{[(tert-butoxy)carbonyl]amino}propanoate

Chemical Property:

• PSA: 64.63000
• LogP: 1.85520
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

Ethyl3-([(tert-butoxy)carbonyl]amino)propanoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Ethyl 3-([(tert-butoxy)carbonyl]amino)propanoate

Technology Process of ethyl 3-{[(tert-butoxy)carbonyl]amino}propanoate

There total 7 articles about ethyl 3-{[(tert-butoxy)carbonyl]amino}propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

di-tert-butyl dicarbonate (24424-99-5) → 3-tert-butoxycarbonylamino-propionic acid ethyl ester (88574-53-2)

Guidance literature:

ethyl β-alaninate hydrochloride; With triethylamine; In acetonitrile; at 20 ℃; for 0.3h;

di-tert-butyl dicarbonate; zirconium(IV) chloride; In acetonitrile; at 20 ℃; for 2h;

Reference yield: 99.0%

di-tert-butyl dicarbonate (24424-99-5) + ethyl β-alaninate hydrochloride (4244-84-2) → 3-tert-butoxycarbonylamino-propionic acid ethyl ester (88574-53-2)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 0 - 60 ℃; for 6h;

Reference yield: 95.0%

ethanol (64-17-5) + 3-(tert-butyloxycarbonylamino)propionic acid (3303-84-2) → 3-tert-butoxycarbonylamino-propionic acid ethyl ester (88574-53-2)

Guidance literature:

With dmap; dacarbazine; at 23 ℃; for 16h;

DOI:10.1016/S0040-4039(03)00453-2

upstream raw materials:

ethanol

3-(tert-butyloxycarbonylamino)propionic acid

3-amino-propionic acid ethyl ester

di-tert-butyl dicarbonate

Downstream raw materials:

3-(tert-butyloxycarbonylamino)propionic acid

(2-carbamoyl-ethyl)-carbamic acid tert-butyl ester

(2-hydrazinocarbonyl-ethyl)-carbamic acid tert-butyl ester

methyl 3-tert-butoxycarbonylaminopropionate