5-(Bromomethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole

Base Information

Chemical Name:5-(Bromomethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole
CAS No.:439134-78-8
Molecular Formula:C12H9BrF3NS
Molecular Weight:336.175
Hs Code.:2934100090
DSSTox Substance ID:DTXSID50383274
Wikidata:Q72447403
Mol file:439134-78-8.mol

Synonyms:439134-78-8;5-(bromomethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole;5-(Bromomethyl)-4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole;C12H9BrF3NS;SCHEMBL1553917;DTXSID50383274;MFCD04115403;Thiazole, 5-(bromomethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-;AKOS016004397;DS-16618;FT-0619695;EN300-253514;F53168;A924200;5-Bromomethyl-4-methyl-2-(4-trifluoromethyl-phenyl)-thiazole;5-(Bromomethyl)-4-methyl-2-(4-(trifluoromethyl)-phenyl)thiazole

Suppliers and Price of 5-(Bromomethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
5-Bromomethyl-4-methyl-2-(4-trifluoromethylphenyl)thiazole
250 mg
$ 144.00

SynQuest Laboratories
5-Bromomethyl-4-methyl-2-(4-trifluoromethylphenyl)thiazole
1 g
$ 407.00

Matrix Scientific
5-(Bromomethyl)-4-methyl-2-(4-(trifluoromethyl)-phenyl)thiazole 95+%
250mg
$ 364.00

Matrix Scientific
5-(Bromomethyl)-4-methyl-2-(4-(trifluoromethyl)-phenyl)thiazole 95+%
1g
$ 807.00

Crysdot
5-(Bromomethyl)-4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole 95+%
1g
$ 223.00

Crysdot
5-(Bromomethyl)-4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole 95+%
5g
$ 955.00

Chemenu
5-(bromomethyl)-4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole 95%
5g
$ 903.00

Chemenu
5-(bromomethyl)-4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole 95%
1g
$ 211.00

Apolloscientific
5-Bromomethyl-4-methyl-2-(4-trifluoromethyl-phenyl)-thiazole
250mg
$ 90.00

Apolloscientific
5-Bromomethyl-4-methyl-2-(4-trifluoromethyl-phenyl)-thiazole
1g
$ 254.00

Total 21 raw suppliers

Chemical Property of 5-(Bromomethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole

Chemical Property:

Vapor Pressure:1.89E-05mmHg at 25°C
Melting Point:64 °C
Boiling Point:373.7°C at 760 mmHg
PKA:1.58±0.10(Predicted)
Flash Point:179.8°C
PSA：41.13000
Density:1.551g/cm³
LogP:5.03220
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:4.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:334.95912
Heavy Atom Count:18
Complexity:279

Purity/Quality:

97% ^*data from raw suppliers

5-Bromomethyl-4-methyl-2-(4-trifluoromethylphenyl)thiazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(SC(=N1)C2=CC=C(C=C2)C(F)(F)F)CBr

Technology Process of 5-(Bromomethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole

There total 5 articles about 5-(Bromomethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 317318-96-0
[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-yl]-methanol

: 439134-78-8
5-(bromomethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole

Guidance literature:: With phosphorus tribromide; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1021/jm058056x

Reference yield: 96.0%

: 439134-78-8
5-(bromomethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole

Guidance literature:

Reference yield:

: 175277-03-9
4-methyl-2-[4-(trifluoromethyl)phenyl]thiazole-5-carboxylic acid ethyl ester

: 439134-78-8
5-(bromomethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 80.2 g / LiAlH₄ / tetrahydrofuran / 1.3 h / 20 °C

2: 97 percent / PBr₃ / CH₂Cl₂ / 2 h / 20 °C

With lithium aluminium tetrahydride; phosphorus tribromide; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm058056x