Hesperetin Triacetate

Base Information

• Chemical Name: Hesperetin Triacetate
• CAS No.: 73489-97-1
• Molecular Formula: C₂₂H₂₀O₉
• Molecular Weight: 428.395
• Mol file: 73489-97-1.mol

Synonyms:Hesperetin Triacetate;(S)-5,7-Bis(acetyloxy)-2-[3-(acetyloxy)-4-Methoxyphenyl]-2,3-dihydro-4H-1-benzopyran-4-one;Tri-O-acetylhesperetin

Chemical Property of Hesperetin Triacetate

Chemical Property:

• PSA: 114.43000
• LogP: 3.17760
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

rac-HesperetinTriacetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Hesperetin Triacetate

There total 3 articles about Hesperetin Triacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetic anhydride (108-24-7) + hesperetin (520-33-2,41001-90-5,69097-99-0) → (S)-5,7-diacetoxy-2-(3-acetoxy-4-methoxy-phenyl)-chroman-4-one (6274-73-3,73489-97-1)

Guidance literature:

With pyridine; at 20 ℃; Inert atmosphere;

DOI:10.1055/s-0031-1290756

Reference yield:

hesperidin (520-26-3) → (S)-5,7-diacetoxy-2-(3-acetoxy-4-methoxy-phenyl)-chroman-4-one (6274-73-3,73489-97-1)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous sulfuric acid

2: pyridine

With pyridine; sulfuric acid;

Reference yield:

acetyl chloride (75-36-5) + hesperetin (520-33-2,41001-90-5,69097-99-0) → (S)-5,7-diacetoxy-2-(3-acetoxy-4-methoxy-phenyl)-chroman-4-one (6274-73-3,73489-97-1)

Guidance literature:

With pyridine;

upstream raw materials:

acetyl chloride

hesperetin

hesperidin

acetic anhydride

Downstream raw materials:

4'-O-methyl-8-isoprenyl eriodictyol

2-(3-acetoxy-4-methoxyphenyl)-7-hydroxy-4-oxochroman-5-yl acetate

Refernces