3-(2,6-Dichlorophenyl)-1-(4-methylphenyl)prop-2-en-1-one

Base Information

Chemical Name:3-(2,6-Dichlorophenyl)-1-(4-methylphenyl)prop-2-en-1-one
CAS No.:146497-07-6
Molecular Formula:C16H12Cl2O
Molecular Weight:291.17
Hs Code.:
European Community (EC) Number:653-651-3
Nikkaji Number:J1.832.856I
Wikidata:Q76305810
ChEMBL ID:CHEMBL17063
Mol file:146497-07-6.mol

Synonyms:3-(2,6-Dichlorophenyl)-1-(4-methylphenyl)prop-2-en-1-one;(E)-3-(2,6-dichlorophenyl)-1-(4-methylphenyl)prop-2-en-1-one;146497-07-6;CHEMBL17063;SCHEMBL979659;RFYXNLVUTQPPOO-MDZDMXLPSA-N;(alphaE)-beta-(2,6-Dichlorophenyl)-4'-methylacrylophenone;(2E)-3-(2,6-Dichlorophenyl)-1-(4-methylphenyl)-2-propen-1-one #

Suppliers and Price of 3-(2,6-Dichlorophenyl)-1-(4-methylphenyl)prop-2-en-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
2,6-DICHLORO-4'-METHYLCHALCONE Aldrich
250mg
$ 57.00

American Custom Chemicals Corporation
3-(2,6-DICHLOROPHENYL)-1-(4-METHYLPHENYL)PROP-2-EN-1-ONE 95.00%
250MG
$ 727.65

Total 2 raw suppliers

Chemical Property of 3-(2,6-Dichlorophenyl)-1-(4-methylphenyl)prop-2-en-1-one

Chemical Property:

PSA：0.00000
LogP:0.00000
XLogP3:5.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:290.0265204
Heavy Atom Count:19
Complexity:322

Purity/Quality:

97% ^*data from raw suppliers

2,6-DICHLORO-4'-METHYLCHALCONE Aldrich ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C(=O)C=CC2=C(C=CC=C2Cl)Cl
Isomeric SMILES:CC1=CC=C(C=C1)C(=O)/C=C/C2=C(C=CC=C2Cl)Cl

Technology Process of 3-(2,6-Dichlorophenyl)-1-(4-methylphenyl)prop-2-en-1-one

There total 1 articles about 3-(2,6-Dichlorophenyl)-1-(4-methylphenyl)prop-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 83-38-5
2,6-dichlorobenzaldehyde

: 122-00-9
para-methylacetophenone

: 146497-07-6
3-(2,6-dichloro-phenyl)-1-p-tolyl-propenone

Guidance literature:: With potassium hydroxide; In ethanol; at 5 - 20 ℃; for 10h;
DOI:10.1016/S0960-894X(02)00832-6

Reference yield: 80.0%

: 146497-07-6
3-(2,6-dichloro-phenyl)-1-p-tolyl-propenone

: 1616723-43-3
(E)-3-(2,6-dichlorophenyl)-1-(p-tolyl)prop-2-en-1-ol

Guidance literature:: With methanol; sodium tetrahydroborate; cerium(III) chloride heptahydrate; at 0 - 20 ℃; for 1h;
DOI:10.1039/c4ob00526k

Reference yield:

: 146497-07-6
3-(2,6-dichloro-phenyl)-1-p-tolyl-propenone

: 1622061-44-2
(E)-N-(3-(2,6-dichlorophenyl)-1-(p-tolyl)allyl)-4-methylbenzenesulfonamide

: (E)-N-(3-(2,6-dichlorophenyl)-1-(p-tolyl)allyl)-4-methylbenzenesulfonamide

: 1616723-72-8
(E)-N-(1-(2,6-dichlorophenyl)-3-(p-tolyl)allyl)-4-methylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: cerium(III) chloride heptahydrate; sodium tetrahydroborate; methanol / 1 h / 0 - 20 °C

2: (S)-(+)-[3,3'-bis(diphenylmethyl)-1,1’-binaphthalen-2,2’-yl]-N-triflylphosphoramide / chloroform / 10 h / -60 °C / Inert atmosphere; Schlenk technique

With methanol; sodium tetrahydroborate; cerium(III) chloride heptahydrate; (S)-(+)-[3,3'-bis(diphenylmethyl)-1,1’-binaphthalen-2,2’-yl]-N-triflylphosphoramide; In chloroform;
DOI:10.1039/c4ob00526k