2,6-Dichlorobenzaldehyde

Base Information

• Chemical Name: 2,6-Dichlorobenzaldehyde
• CAS No.: 83-38-5
• Molecular Formula: C7H4Cl2O
• Molecular Weight: 175.014
• Hs Code.: 29130000
• European Community (EC) Number: 201-472-2
• NSC Number: 7193
• UN Number: 1759
• UNII: 781ADM5611
• DSSTox Substance ID: DTXSID5024970
• Nikkaji Number: J60.295G
• Wikidata: Q27266626
• ChEMBL ID: CHEMBL1442731
• Mol file: 83-38-5.mol

Synonyms:2,6-DICHLOROBENZALDEHYDE;83-38-5;Benzaldehyde, 2,6-dichloro-;2,6-dichloro benzaldehyde;CCRIS 6014;NSC 7193;EINECS 201-472-2;MFCD00003307;2,6-dichloro-benzaldehyde;DTXSID5024970;UNII-781ADM5611;NSC-7193;781ADM5611;2,6-Dichloro-Benzaldehyd;2,6-dichlorbenzaldehyd;NSC7193;2,6dichloro-benzaldehyde;Benzaldehyde,6-dichloro-;2,6-dichloro -benzaldehyde;SCHEMBL96214;MLS002415691;(2,6-dichlorophenyl)methanone;DTXCID304970;CHEMBL1442731;2,6-Dichlorobenzaldehyde, 99%;O,O'-DICHLOROBENZALDEHYDE;HMS3039H11;Tox21_200742;BBL023680;STK199280;AKOS000119432;CS-W007684;LS-1824;PS-6006;CAS-83-38-5;NCGC00091746-01;NCGC00091746-02;NCGC00091746-03;NCGC00258296-01;SMR001370881;AM20060735;D0331;FT-0610593;EN300-18410;D70634;2,6-Dichlorobenzaldehyde, purum, >=99.0% (T);A840567;Q-200208;Q27266626;Z57773430;F3098-5169

Chemical Property of 2,6-Dichlorobenzaldehyde

Chemical Property:

• Appearance/Colour: white to light yellow powder
• Vapor Pressure: 0.0406mmHg at 25°C
• Melting Point: 69-71 °C(lit.)
• Refractive Index: 1.6
• Boiling Point: 239.2 °C at 760 mmHg
• Flash Point: 97.4 °C
• PSA: 17.07000
• Density: 1.4 g/cm³
• LogP: 2.80590
• Storage Temp.: Store below +30°C.
• Sensitive.: Air Sensitive
• Solubility.: <1g/l insoluble
• Water Solubility.: <0.1 g/100 mL at 23℃
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 173.9639201
• Heavy Atom Count: 10
• Complexity: 117
• Transport DOT Label: Corrosive

Purity/Quality:

≥99% ^*data from raw suppliers

2,6-Dichlorobenzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C, Xi
• Hazard Codes: C,Xi
• Statements: 34-36/37/38
• Safety Statements: 26-27-28-36/37/39-45-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Classes -> Benzaldehydes
• Canonical SMILES: C1=CC(=C(C(=C1)Cl)C=O)Cl
• Uses: An intermediate in the synthesis of substituted (2,6-dichlorobenzylideneamino)guanidines and some hydrazone derivatives of C-cyanoformamidrazone. It An intermediate in the synthesis of substituted (2,6-dichlorobenzylideneamino)guanidines and some hydrazone derivatives of C-cyanoformamidrazone. It showed antihypertensive activity.

Technology Process of 2,6-Dichlorobenzaldehyde

There total 45 articles about 2,6-Dichlorobenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2,6-dichlorobenzyl alcohol (15258-73-8) → 2,6-dichlorobenzaldehyde (83-38-5)

Guidance literature:

With dmap; tetrakis(actonitrile)copper(I) hexafluorophosphate; N,N'-di-tert-butylethylenediamine; oxygen; In dichloromethane; at 20 ℃; for 3h; under 760.051 Torr; Schlenk technique; Molecular sieve; Sealed tube;

DOI:10.1002/anie.201411483

Reference yield: 98.0%

2,6-Dichlorobenzaldehyde N,N-dimethylhydrazone (2828-47-9) → 2,6-dichlorobenzaldehyde (83-38-5)

Guidance literature:

With 3-benzyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride; In chloroform; at 20 ℃; for 1h;

Reference yield: 98.0%

2,6-dichlorobenzaldoxime (25185-95-9) → 2,6-dichlorobenzaldehyde (83-38-5)

Guidance literature:

With Cr-MCM-41 zeolite on silica gel; for 0.1h; microwave irradiation;

DOI:10.1081/SCC-120005429

upstream raw materials:

2,6-dichlorotoluene

2,6-dichloro-benzaldehyde-[N-(4-dimethylamino-phenyl)-oxime ]

2,6-dichlorobenzalchloride

guanabenz

Downstream raw materials:

3t-(2,6-dichloro-phenyl)-2-methyl-acrylic acid

nicotinic acid-(2,6-dichloro-benzylidenehydrazide)

(2E)-3-(2,6-dichlorophenyl)prop-2-enoic acid

1,1-diacetoxy-1-(2,6-dichlorophenyl)methane