Pipradimadol

Base Information

Chemical Name:Pipradimadol
CAS No.:68797-29-5
Molecular Formula:C₂₄H₃₇ClN₂O₂
Molecular Weight:421.023
Hs Code.:
Mol file:68797-29-5.mol

Synonyms:2-(1-o-chlorophenethyl-4-hydroxy-4-piperidyl)-N-cyclohexyl-N-methyl isobutyric acid amide;Pipothiazine palmitate;2-[1-(3-{2-[(dimethylamino)sulfonyl]-10H-phenothiazin-10-yl}propyl)piperidin-4-yl]ethyl palmitate;Pipotiazine palmitate [USAN];PIPOTIAZINE PALMITATE;pipradimadol;

Suppliers and Price of Pipradimadol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
PIPRADIMADOL 95.00%
5MG
$ 504.56

Total 5 raw suppliers

Chemical Property of Pipradimadol

Chemical Property:

Vapor Pressure:1.57E-13mmHg at 25°C
Boiling Point:563.4°Cat760mmHg
Flash Point:294.5°C
PSA：43.78000
Density:1.15g/cm³
LogP:4.46460

Purity/Quality:

99% ^*data from raw suppliers

PIPRADIMADOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Pipradimadol

There total 6 articles about Pipradimadol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13078-80-3
2-(2-chlorophenyl)ethanamine

: 68797-29-5
2-(1-o-chlorophenethyl-4-hydroxy-4-piperidyl)-N-cyclohexyl-N-methyl isobutyric acid amide

Guidance literature:: Multi-step reaction with 4 steps

1: 98.7 percent / acetic acid / 6 h / 60 °C

2: Na, propanol / 1 h / Heating

3: conc. HCl / propan-2-ol; H₂O / 6 h / 20 - 130 °C

4: 1.) LDA / 1.) THF, hexane, -75 deg C, 20 min, 2.) THF, hexane, -75 deg C, 30 min

With hydrogenchloride; propan-1-ol; sodium; acetic acid; lithium diisopropyl amide; In water; isopropyl alcohol;
DOI:10.1021/jm00355a010

Reference yield:

: 100-60-7
N-methylcyclohexylamine

: 68797-29-5
2-(1-o-chlorophenethyl-4-hydroxy-4-piperidyl)-N-cyclohexyl-N-methyl isobutyric acid amide

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / CHCl₃ / 1 h / 20 °C

2: 1.) LDA / 1.) THF, hexane, -75 deg C, 20 min, 2.) THF, hexane, -75 deg C, 30 min

With triethylamine; lithium diisopropyl amide; In chloroform;
DOI:10.1021/jm00355a010

Reference yield:

: 1-[2-(2-Chloro-phenyl)-ethyl]-4-oxo-piperidine-3-carboxylic acid ethyl ester

: 68797-29-5
2-(1-o-chlorophenethyl-4-hydroxy-4-piperidyl)-N-cyclohexyl-N-methyl isobutyric acid amide

Guidance literature:: Multi-step reaction with 2 steps

1: conc. HCl / propan-2-ol; H₂O / 6 h / 20 - 130 °C

2: 1.) LDA / 1.) THF, hexane, -75 deg C, 20 min, 2.) THF, hexane, -75 deg C, 30 min

With hydrogenchloride; lithium diisopropyl amide; In water; isopropyl alcohol;
DOI:10.1021/jm00355a010