3-Cyclohexylpropan-1-amine hydochloride

Base Information

• Chemical Name: 3-Cyclohexylpropan-1-amine hydochloride
• CAS No.: 90726-03-7
• Molecular Formula: C9H20ClN
• Molecular Weight: 177.717
• Hs Code.: 2921300090
• Mol file: 90726-03-7.mol

Synonyms:3-Cyclohexylpropan-1-amine hydochloride

Chemical Property of 3-Cyclohexylpropan-1-amine hydochloride

Chemical Property:

• PSA: 26.02000
• LogP: 3.80790

Purity/Quality:

3-Cyclohexylpropan-1-amine hydochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Cyclohexylpropan-1-amine hydochloride

There total 2 articles about 3-Cyclohexylpropan-1-amine hydochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

N-[3-cyclohexylprop-1-yl]phthalimide (144290-77-7) → 3-cyclohexylpropanamine hydrochloride (90726-03-7)

Guidance literature:

N-[3-cyclohexylprop-1-yl]phthalimide; With hydrazine hydrate; In ethanol; for 3h; Reflux;

With hydrogenchloride; In water;

DOI:10.1016/j.bmc.2011.03.046

Reference yield:

3-cyclohexylpropan-1-ol (1124-63-6) → 3-cyclohexylpropanamine hydrochloride (90726-03-7)

Guidance literature:

Multi-step reaction with 2 steps

1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 0 - 20 °C

2: hydrazine hydrate / ethanol / 3 h / Reflux

With hydrazine hydrate; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; 1: Mitsunobu reaction;

DOI:10.1016/j.bmc.2011.03.046

Reference yield:

3-cyclohexylpropanamine hydrochloride (90726-03-7) + trichloromethyl chloroformate (503-38-8) → C10H17NO (93489-29-3)

Guidance literature:

With pyrographite; In ethyl acetate; Reflux;

DOI:10.1016/j.bmc.2011.03.046

upstream raw materials:

3-cyclohexylpropan-1-ol

N-[3-cyclohexylprop-1-yl]phthalimide

Downstream raw materials:

3-(1H-imidazol-4-yl)propyl 3-cyclohexylpropylcarbamate hydrogen maleate

C₁₀H₁₇NO