3-(1H-imidazol-4-yl)propyl 3-cyclohexylpropylcarbamate hydrogen maleate

Base Information

• Chemical Name: 3-(1H-imidazol-4-yl)propyl 3-cyclohexylpropylcarbamate hydrogen maleate
• CAS No.: 454646-67-4
• Molecular Formula: C₁₆H₂₇N₃O₂
• Molecular Weight: 293.409
• Mol file: 454646-67-4.mol

Synonyms:3-(1H-imidazol-4-yl)propyl 3-cyclohexylpropylcarbamate hydrogen maleate

Chemical Property of 3-(1H-imidazol-4-yl)propyl 3-cyclohexylpropylcarbamate hydrogen maleate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(1H-imidazol-4-yl)propyl 3-cyclohexylpropylcarbamate hydrogen maleate

There total 5 articles about 3-(1H-imidazol-4-yl)propyl 3-cyclohexylpropylcarbamate hydrogen maleate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C10H17NO (93489-29-3) + 3-(1H-imidazol-4-yl)-propan-1-ol hydrochloride → 3-(1H-imidazol-4-yl)propyl 3-cyclohexylpropylcarbamate hydrogen maleate (454646-67-4)

Guidance literature:

C₁₀H₁₇NO; 3-(1H-imidazol-4-yl)-propan-1-ol hydrochloride; In acetonitrile; Reflux;

With ammonia; In methanol; dichloromethane;

DOI:10.1016/j.bmc.2011.03.046

Reference yield:

3-cyclohexylpropanamine hydrochloride (90726-03-7) → 3-(1H-imidazol-4-yl)propyl 3-cyclohexylpropylcarbamate hydrogen maleate (454646-67-4)

Guidance literature:

Multi-step reaction with 2 steps

1: pyrographite / ethyl acetate / Reflux

2: acetonitrile / Reflux

With pyrographite; In ethyl acetate; acetonitrile;

DOI:10.1016/j.bmc.2011.03.046

Reference yield:

3-cyclohexylpropan-1-ol (1124-63-6) → 3-(1H-imidazol-4-yl)propyl 3-cyclohexylpropylcarbamate hydrogen maleate (454646-67-4)

Guidance literature:

Multi-step reaction with 4 steps

1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 0 - 20 °C

2: hydrazine hydrate / ethanol / 3 h / Reflux

3: pyrographite / ethyl acetate / Reflux

4: acetonitrile / Reflux

With pyrographite; hydrazine hydrate; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; ethyl acetate; acetonitrile; 1: Mitsunobu reaction;

DOI:10.1016/j.bmc.2011.03.046

upstream raw materials:

C₁₀H₁₇NO

3-cyclohexylpropanamine hydrochloride

3-cyclohexylpropan-1-ol

N-[3-cyclohexylprop-1-yl]phthalimide