3,5-Difluoro-2-hydroxyphenylboronic acid

Base Information

Chemical Name:3,5-Difluoro-2-hydroxyphenylboronic acid
CAS No.:1150114-51-4
Molecular Formula:C6H5BF2O3
Molecular Weight:173.912
Hs Code.:2931900090
DSSTox Substance ID:DTXSID90402539
Wikidata:Q82205960
Mol file:1150114-51-4.mol

Synonyms:1150114-51-4;(3,5-difluoro-2-hydroxyphenyl)boronic acid;3,5-Difluoro-2-hydroxyphenylboronic acid;Boronic acid, B-(3,5-difluoro-2-hydroxyphenyl)-;SCHEMBL3234924;DTXSID90402539;MFCD03095356;AKOS006344771;CS-16702;(3,5-difluoro-2-hydroxyphenyl)boronicacid;CS-0102470;FT-0745223;6-(5-Nitrofuran-2-yl)pyridazin-3(2H)-one;D71381;EN300-1722404;A894066

Suppliers and Price of 3,5-Difluoro-2-hydroxyphenylboronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,5-Difluoro-2-hydroxyphenylboronicacid
100mg
$ 150.00

TRC
3,5-Difluoro-2-hydroxyphenylboronicacid
25mg
$ 50.00

Crysdot
(3,5-Difluoro-2-hydroxyphenyl)boronicacid 95+%
1g
$ 475.00

Chemenu
(3,5-Difluoro-2-hydroxyphenyl)boronicacid 95+%
1g
$ 202.00

AOBChem
3,5-Difluoro-2-hydroxyphenylboronicacid 97%
500mg
$ 183.00

American Custom Chemicals Corporation
3,5-DIFLUORO-2-HYDROXYPHENYLBORONIC ACID 95.00%
1G
$ 488.25

Ambeed
(3,5-Difluoro-2-hydroxyphenyl)boronicacid 98%
1g
$ 216.00

Ambeed
(3,5-Difluoro-2-hydroxyphenyl)boronicacid 98%
250mg
$ 102.00

Ambeed
(3,5-Difluoro-2-hydroxyphenyl)boronicacid 98%
100mg
$ 66.00

Total 18 raw suppliers

Chemical Property of 3,5-Difluoro-2-hydroxyphenylboronic acid

Chemical Property:

Boiling Point:318.4±52.0 °C(Predicted)
PKA:6.54±0.58(Predicted)
PSA：60.69000
Density:1.52±0.1 g/cm3(Predicted)
LogP:-0.64980
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:174.0299805
Heavy Atom Count:12
Complexity:158

Purity/Quality:

97% ^*data from raw suppliers

3,5-Difluoro-2-hydroxyphenylboronicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=CC(=CC(=C1O)F)F)(O)O
Uses 3,5-Difluoro-2-hydroxyphenylboronic acid

Technology Process of 3,5-Difluoro-2-hydroxyphenylboronic acid

There total 1 articles about 3,5-Difluoro-2-hydroxyphenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 737000-76-9
(3,5-difluoro-2-methoxyphenyl)boronic acid

: 1150114-51-4
(3,5-difluoro-2-hydroxyphenyl)boronic acid

Guidance literature:: (3,5-difluoro-2-methoxyphenyl)boronic acid; With boron tribromide; In dichloromethane; at 0 ℃; for 2h;

With water; In dichloromethane; Cooling with ice;

Reference yield: 84.0%

: 1150114-51-4
(3,5-difluoro-2-hydroxyphenyl)boronic acid

: 1565836-98-7
C₁₉H₁₅ClN₂O₂

: 1565837-14-0
1-(2-(3,5-difluoro-2-hydroxyphenyl)-4-methyl-6-(3-phenoxyphenyl)pyrimidin-5-yl)ethanone

Guidance literature:: (3,5-difluoro-2-hydroxyphenyl)boronic acid; C₁₉H₁₅ClN₂O₂; In 1,4-dioxane; at 20 ℃; for 0.0833333h; Inert atmosphere;

With palladium diacetate; sodium carbonate; triphenylphosphine; In 1,4-dioxane; at 20 - 110 ℃; for 3.5h; Inert atmosphere;
DOI:10.1016/j.tetlet.2014.01.042

Reference yield: 73.0%

: 1150114-51-4
(3,5-difluoro-2-hydroxyphenyl)boronic acid

: 1567215-32-0
(S)-methyl 2-(7-(4-(allyloxy)-4-methylpiperidin-1-yl)-2-(3-bromophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate

: (S)-methyl 2-(7-(4-(allyloxy)-4-methylpiperidin-1-yl)-2-(2',4'-difluoro-6‘-hydroxy-[1,1‘-biphenyl]-3-yl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tertbutoxy)acetate

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In water; N,N-dimethyl-formamide; at 90 ℃; for 3h; Inert atmosphere;