5,7-Dichloro-1-Methyl-1H-...

Base Information

• Chemical Name: 5,7-Dichloro-1-Methyl-1H-...
• CAS No.: 939979-32-5
• Molecular Formula: C6H4Cl2N4
• Molecular Weight: 203.031
• Hs Code.: 2933990090
• Mol file: 939979-32-5.mol

Synonyms:5,7-Dichloro-1-Methyl-1H-...;5,7-Dichloro-1-Methyl-1H-pyrazolo[4,3-d]pyriMidine;1H-Pyrazolo[4,3-d]pyriMidine, 5,7-dichloro-1-Methyl-

Chemical Property of 5,7-Dichloro-1-Methyl-1H-...

Chemical Property:

• PSA: 43.60000
• LogP: 1.67010
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C

Purity/Quality:

97% ^*data from raw suppliers

5,7-dichloro-1-methyl-1H-pyrazolo[4,3-d]pyrimidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5,7-Dichloro-1-Methyl-1H-...

There total 11 articles about 5,7-Dichloro-1-Methyl-1H-... which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.2%

1-methyl-1H-pyrazolo[4,3-d]pyrimidine-5,7-(4H,6H)-dione (83824-38-8) → 5,7-dichloro-1-methyl-1H-pyrazolo[4,3-d]pyrimidine (939979-32-5)

Guidance literature:

With N,N-diethylaniline; trichlorophosphate; at 130 ℃; for 18h; Inert atmosphere;

Reference yield: 60.0%

1-methylpyrazolo[4,3-d]pyrimidine-5,7-diol (83824-38-8) → 5,7-dichloro-1-methyl-1H-pyrazolo[4,3-d]pyrimidine (939979-32-5)

Guidance literature:

With N,N-diethylaniline; trichlorophosphate; at 110 ℃; for 4h;

Reference yield:

C6H8N4O2 → 5,7-dichloro-1-methyl-1H-pyrazolo[4,3-d]pyrimidine (939979-32-5)

Guidance literature:

With N,N-diethylaniline; trichlorophosphate; for 22h; Heating / reflux;

upstream raw materials:

1-methyl-1H-pyrazolo[4,3-d]pyrimidine-5,7-(4H,6H)-dione

1,1'-carbonyldiimidazole

4-amino-1-methyl-1H-pyrazole-5-carboxamide

1-methyl-4-nitro-1H-pyrazole-5-carboxamide

Downstream raw materials:

C₁₃H₁₀Cl₃N₅

(S)-1-ethyl-3-(4-(1-methyl-7-(3-methylmorpholino)-1H-pyrazolo[4,3-d]pyrimidin-5-yl)phenyl)urea

(S)-1-ethyl-3-(4-(7-(3-ethylmorpholino)-1-methyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)phenyl)urea

1-(4-(7-((1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl)-1-methyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)phenyl)-3-ethylurea