4-amino-1-methyl-1H-pyrazole-5-carboxamide

Base Information

Chemical Name:4-amino-1-methyl-1H-pyrazole-5-carboxamide
CAS No.:92534-73-1
Molecular Formula:C5H8N4O
Molecular Weight:140.145
Hs Code.:2933199090
European Community (EC) Number:835-982-7
DSSTox Substance ID:DTXSID70424496
Wikidata:Q82237095
Mol file:92534-73-1.mol

Synonyms:4-amino-1-methyl-1H-pyrazole-5-carboxamide;92534-73-1;4-amino-2-methylpyrazole-3-carboxamide;4-Amino-2-methyl-2H-pyrazole-3-carboxylic acid amide;1H-Pyrazole-5-carboxamide, 4-amino-1-methyl-;SCHEMBL2099625;DTXSID70424496;QGURFMMGHWBSEV-UHFFFAOYSA-N;BBL039385;MFCD00464001;STK315319;AKOS000305041;AS-36552;4-Amino-2-methyl-2H-pyrazole-3-carboxamide;BB 0259826;CS-0094671;FT-0677927;EN300-110134;4-amino-2-methyl-2h-pyrazole-3-carboxylic acidamide;4-amino-2-methyl-2 h-pyrazole-3-carboxylic acid amide;4-Amino-2-methyl-2H-pyrazole-3-carboxylic acid amide, AldrichCPR

Suppliers and Price of 4-amino-1-methyl-1H-pyrazole-5-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Amino-1-methyl-1H-pyrazole-5-carboxamide
100mg
$ 65.00

Matrix Scientific
4-Amino-2-methyl-2H-pyrazole-3-carboxylic acid amide
500mg
$ 156.00

Crysdot
4-Amino-1-methyl-1H-pyrazole-5-carboxamide 95+%
5g
$ 668.00

Chemenu
4-Amino-1-methyl-1H-pyrazole-5-carboxamide 95+%
5g
$ 1888.00

ChemBridge Corporation
4-amino-1-methyl-1H-pyrazole-5-carboxamide 95%
250 mg
$ 84.00

Biosynth Carbosynth
4-Amino-1-methyl-1H-pyrazole-5-carboxamide
250 mg
$ 115.00

Biosynth Carbosynth
4-Amino-1-methyl-1H-pyrazole-5-carboxamide
100 mg
$ 58.00

Biosynth Carbosynth
4-Amino-1-methyl-1H-pyrazole-5-carboxamide
500 mg
$ 200.00

Biosynth Carbosynth
4-Amino-1-methyl-1H-pyrazole-5-carboxamide
1 g
$ 340.00

Biosynth Carbosynth
4-Amino-1-methyl-1H-pyrazole-5-carboxamide
2 g
$ 578.00

Total 13 raw suppliers

Chemical Property of 4-amino-1-methyl-1H-pyrazole-5-carboxamide

Chemical Property:

Vapor Pressure:3.2E-05mmHg at 25°C
Boiling Point:355.1oC at 760 mmHg
Flash Point:168.6oC
PSA：86.93000
Density:1.56g/cm3
LogP:0.38270
XLogP3:-0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:140.06981089
Heavy Atom Count:10
Complexity:149

Purity/Quality:

99% ^*data from raw suppliers

4-Amino-1-methyl-1H-pyrazole-5-carboxamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=C(C=N1)N)C(=O)N

Technology Process of 4-amino-1-methyl-1H-pyrazole-5-carboxamide

There total 6 articles about 4-amino-1-methyl-1H-pyrazole-5-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 92534-72-0
1-methyl-4-nitro-1H-pyrazole-5-carboxamide

: 92534-73-1
4-amino-1-methyl-1H-pyrazole-5-carboxamide

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 12h; under 775.743 Torr;

Reference yield:

: 16034-46-1
1-methyl-1H-pyrazole-5-carboxylic acid

: 92534-73-1
4-amino-1-methyl-1H-pyrazole-5-carboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / nitric acid (d 1.52), sulfuric acid monohydrate / 1.) 30-40 deg C, 1 h; 2.) 75-80 deg C, 2 h

2: 1.) thionyl chloride; 2.) 25percent aqueous ammonia / 1.) reflux, 4 h; 2.) 10 deg C

3: 84 percent / 95percent hydrazine hydrate / Raney nickel / propan-2-ol / 55 - 60 °C

With ammonium hydroxide; thionyl chloride; sulfuric acid; nitric acid; hydrazine hydrate; nickel; In isopropyl alcohol;

Reference yield:

: 92534-69-5
1-methyl-4-nitro-1H-pyrazole-5-carboxylic acid

: 92534-73-1
4-amino-1-methyl-1H-pyrazole-5-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) thionyl chloride; 2.) 25percent aqueous ammonia / 1.) reflux, 4 h; 2.) 10 deg C

2: 84 percent / 95percent hydrazine hydrate / Raney nickel / propan-2-ol / 55 - 60 °C

With ammonium hydroxide; thionyl chloride; hydrazine hydrate; nickel; In isopropyl alcohol;