p-Fluorophenyldichlorophosphine

Base Information

Chemical Name:p-Fluorophenyldichlorophosphine
CAS No.:5510-93-0
Molecular Formula:C6H4Cl2FP
Molecular Weight:196.976
Hs Code.:2903999090
DSSTox Substance ID:DTXSID70500380
Nikkaji Number:J149.696D
Wikidata:Q82351929
Mol file:5510-93-0.mol

Synonyms:p-fluorophenyldichlorophosphine;5510-93-0;dichloro-(4-fluorophenyl)phosphane;Dichloro(p-fluorophenyl)phosphine;1,4-Fluorphenyldichlorphosphin;SCHEMBL2886150;DTXSID70500380;XMDBKXFFPNRIQD-UHFFFAOYSA-N;(4-Fluorophenyl)phosphonous dichloride

Suppliers and Price of p-Fluorophenyldichlorophosphine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of p-Fluorophenyldichlorophosphine

Chemical Property:

PSA：13.59000
LogP:3.24050
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:195.9411707
Heavy Atom Count:10
Complexity:102

Purity/Quality:: 99%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1F)P(Cl)Cl

Technology Process of p-Fluorophenyldichlorophosphine

There total 4 articles about p-Fluorophenyldichlorophosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 462-06-6
fluorobenzene

: 5510-93-0
para-fluorophenylphosphonous dichloride

Guidance literature:: With phosphorus trichloride; Lewis acid;

Reference yield:

: 133472-27-2
4-fluorophenylzinc chloride

: 5510-93-0
para-fluorophenylphosphonous dichloride

Guidance literature:: With phosphorus trichloride; In tetrahydrofuran; at -78 - 20 ℃; for 16h; Inert atmosphere; Schlenk technique;
DOI:10.1021/acs.joc.1c01560

Reference yield:

: 460-00-4
1-Bromo-4-fluorobenzene

: 5510-93-0
para-fluorophenylphosphonous dichloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 2 h / -78 °C / Inert atmosphere; Schlenk technique

1.2: 2 h / -78 - 20 °C / Inert atmosphere; Schlenk technique

2.1: phosphorus trichloride / tetrahydrofuran / 16 h / -78 - 20 °C / Inert atmosphere; Schlenk technique

With n-butyllithium; phosphorus trichloride; In tetrahydrofuran; hexane;
DOI:10.1021/acs.joc.1c01560