(4-Fluorophenyl)phosphonic acid

Base Information

Chemical Name:(4-Fluorophenyl)phosphonic acid
CAS No.:349-87-1
Molecular Formula:C6H6 F O3 P
Molecular Weight:176.084
Hs Code.:2931900090
DSSTox Substance ID:DTXSID40506339
Nikkaji Number:J3.178.336D
Wikidata:Q82362042
Mol file:349-87-1.mol

Synonyms:349-87-1;(4-fluorophenyl)phosphonic acid;(4-FLUORO-PHENYL)-PHOSPHONIC ACID;4-fluorophenylphosphonic acid;(4-FLUORO-PHENYL)-PHOSPHONICACID;SCHEMBL1567573;DTXSID40506339;ZCCVDWVYQFJUFD-UHFFFAOYSA-N;AKOS006288848

Suppliers and Price of (4-Fluorophenyl)phosphonic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(4-FLUORO-PHENYL)-PHOSPHONIC ACID 95.00%
5MG
$ 496.20

Total 6 raw suppliers

Chemical Property of (4-Fluorophenyl)phosphonic acid

Chemical Property:

PSA：67.34000
LogP:0.62870
XLogP3:0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:176.00385921
Heavy Atom Count:11
Complexity:171

Purity/Quality:

98%min ^*data from raw suppliers

(4-FLUORO-PHENYL)-PHOSPHONIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1F)P(=O)(O)O

Technology Process of (4-Fluorophenyl)phosphonic acid

There total 7 articles about (4-Fluorophenyl)phosphonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 310-40-7
diethyl (4-fluorophenyl)phosphonate

: 349-87-1
(4-fluorophenyl)phosphonic acid

Guidance literature:: With trimethylsilyl bromide; at 20 ℃;
DOI:10.1016/j.poly.2018.02.030

Reference yield: 88.0%

: 657-81-8
4-fluorophenylphosphonic dichloride

: 349-87-1
(4-fluorophenyl)phosphonic acid

Guidance literature:: With hydrogenchloride; for 8h; Heating;

Reference yield:

: 462-06-6
fluorobenzene

: 349-87-1
(4-fluorophenyl)phosphonic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / PCl₃ / Lewis acid

2: 84 percent / DMSO / CH₂Cl₂ / 0.5 h / -76 °C

3: 88 percent / conc. HCl / 8 h / Heating

With hydrogenchloride; dimethyl sulfoxide; phosphorus trichloride; Lewis acid; In dichloromethane;