2,4-Dibromo-3-methylaniline

Base Information

• Chemical Name: 2,4-Dibromo-3-methylaniline
• CAS No.: 80948-78-3
• Molecular Formula: C₇H₇Br₂N
• Molecular Weight: 264.947
• DSSTox Substance ID: DTXSID80565147
• Nikkaji Number: J37.452K
• Wikidata: Q82450097
• Mol file: 80948-78-3.mol

Synonyms:2,4-Dibromo-3-methylaniline;80948-78-3;(2,4-Dibromo-3-methylphenyl)amine;SCHEMBL2319989;2,4-Dibromo-3-methylbenzenamine;DTXSID80565147;AKOS024259818

Chemical Property of 2,4-Dibromo-3-methylaniline

Chemical Property:

• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 264.89247
• Heavy Atom Count: 10
• Complexity: 118

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=CC(=C1Br)N)Br

Technology Process of 2,4-Dibromo-3-methylaniline

There total 4 articles about 2,4-Dibromo-3-methylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 3.0%

1-amino-3-methylbenzene (108-44-1) → amino-5-bromo-2-toluene (6933-10-4) + 2,4-dibromo-5-methylaniline (67643-51-0) + 2,4-dibromo-3-methylaniline (80948-78-3) + 3-methyl-2,4,6-tribromoaniline (71642-16-5)

Guidance literature:

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In chloroform; at 20 ℃; for 0.5h; Solvent; Temperature;

Reference yield:

3-Methylacetanilide (537-92-8) + bromine (7726-95-6) → amino-5-bromo-2-toluene (6933-10-4) + 2,4-dibromo-3-methylaniline (80948-78-3) + 3-methyl-2,4,6-tribromoaniline (71642-16-5)

Guidance literature:

man nach Verseifung des Reaktionsproduktes; Produkt₅: 2.6-Dibrom-3-amino-toluol;

Reference yield:

amino-5-bromo-2-toluene (6933-10-4) → 2,4-dibromo-5-methylaniline (67643-51-0) + 2,4-dibromo-3-methylaniline (80948-78-3)

Guidance literature:

With N-Bromosuccinimide; acetic acid; at 5 - 20 ℃; for 2h;

upstream raw materials:

3-Methylacetanilide

bromine

amino-5-bromo-2-toluene

1-amino-3-methylbenzene

Downstream raw materials:

2,6-dibromotoluene