(2-Fluorobenzyl)hydrazine hydrochloride

Base Information

• Chemical Name: (2-Fluorobenzyl)hydrazine hydrochloride
• CAS No.: 1216246-45-5
• Molecular Formula: C7H10ClFN2
• Molecular Weight: 176.621
• Hs Code.: 2928000090
• Mol file: 1216246-45-5.mol

Synonyms:(2-Fluorobenzyl)hydrazine hydrochloride

Chemical Property of (2-Fluorobenzyl)hydrazine hydrochloride

Chemical Property:

• PSA: 38.05000
• LogP: 2.68220
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-FluorobenzylhydrazineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-Fluorobenzylhydrazine Hydrochloride has been used as a reactant for the synthesis of acylamino substituted benzylbenzohydrazide derivatives.

Technology Process of (2-Fluorobenzyl)hydrazine hydrochloride

There total 2 articles about (2-Fluorobenzyl)hydrazine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-fluorobenzyl chloride (345-35-7) → (2-fluorobenzyl)hydrazine hydrochloride salt (1216246-45-5)

Guidance literature:

With hydrazine hydrate; In water; at 0 - 30 ℃; for 4h;

Reference yield:

(2-fluorobenzyl)hydrazine (51859-98-4) → (2-fluorobenzyl)hydrazine hydrochloride salt (1216246-45-5)

Guidance literature:

With hydrogenchloride; In diethyl ether;

Reference yield: 99.0%

(2-fluorobenzyl)hydrazine hydrochloride salt (1216246-45-5) + (E)-3-(5-fluoro-4-methoxypyrimidin-2-yl)-1-(isoxazol-3-yl)-3-(methoxy(methyl)amino)prop-2-en-1-one → 3-(3-(5-fluoro-4-methoxypyrimidin-2-yl)-1-(2-fluorobenzyl)-1H-pyrazol-5-yl)isoxazole (1446358-49-1)

Guidance literature:

With potassium carbonate; In methanol; water; at 20 - 25 ℃; for 10h; Inert atmosphere; Large scale;

upstream raw materials:

(2-fluorobenzyl)hydrazine

2-fluorobenzyl chloride

Downstream raw materials:

C₁₇H₁₃FN₆*C₂HF₃O₂

ethyl 1-(2-fluorobenzyl)-5-(oxazol-4-yl)-1H-pyrazole-3-carboxylate

3-(1-(2-fluorobenzyl)-3-(5-fluoropyridin-2-yl)-1H-pyrazol-5-yl)isoxazole

C₁₇H₁₅FN₂O₃

Refernces

• 1、 -. "PHENYLTHIOACETIC ACID DERIVATIVES AND USE THEREOF". Page/Page column 70-71. . Retrieved 2010/02/14.