(E)-2-(4-(2-cyanovinylsulfonyl)phenyl)- 2-methylpropanoic acid

Base Information

Chemical Name:(E)-2-(4-(2-cyanovinylsulfonyl)phenyl)- 2-methylpropanoic acid
CAS No.:1356089-38-7
Molecular Formula:C13H13NO4S
Molecular Weight:279.317
Hs Code.:2926909090
Mol file:1356089-38-7.mol

Synonyms:(E)-2-(4-(2-cyanovinylsulfonyl)phenyl)- 2-methylpropanoic acid

Suppliers and Price of (E)-2-(4-(2-cyanovinylsulfonyl)phenyl)- 2-methylpropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(E)-2-(4-((2-Cyanovinyl)sulfonyl)phenyl)-2-methylpropanoicacid 95+%
1g
$ 668.00

American Custom Chemicals Corporation
(E)-2-(4-((2-CYANOVINYL)SULFONYL)PHENYL)-2-METHYLPROPANOIC ACID 95.00%
5MG
$ 497.56

Total 2 raw suppliers

Chemical Property of (E)-2-(4-(2-cyanovinylsulfonyl)phenyl)- 2-methylpropanoic acid

Chemical Property:

PSA：103.61000
LogP:2.94058
Storage Temp.:2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

(E)-2-(4-((2-Cyanovinyl)sulfonyl)phenyl)-2-methylpropanoicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-2-(4-(2-cyanovinylsulfonyl)phenyl)- 2-methylpropanoic acid

There total 4 articles about (E)-2-(4-(2-cyanovinylsulfonyl)phenyl)- 2-methylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 32454-35-6
2-(4-bromophenyl)-2-methylpropionic acid

: 871-29-4,3721-37-7,3721-38-8
trans-β-chloroacrylonitrile

: 1356089-38-7
2-[4-((E)-2-cyano-ethenesulfonyl)phenyl]-2-methylpropionic acid

Guidance literature:: 2-(4-bromophenyl)-2-methylpropionic acid; With phenyllithium; In tetrahydrofuran; toluene; at -80 ℃; for 0.0833333h; Inert atmosphere;

With n-butyllithium; In tetrahydrofuran; hexane; toluene; for 0.333333h; Inert atmosphere;

trans-β-chloroacrylonitrile; Further stages;
DOI:10.1016/j.bmcl.2012.01.085

Reference yield:

: C₁₀H₁₀O₄S^(2-)*2Li⁽¹⁺⁾

: 920-37-6
2-Chloroacrylonitrile

: 1356089-38-7
2-[4-((E)-2-cyano-ethenesulfonyl)phenyl]-2-methylpropionic acid

Guidance literature:: C₁₀H₁₀O₄S^(2-)*2Li⁽¹⁺⁾; 2-Chloroacrylonitrile; With acetic acid; In methanol; water; at 20 ℃;

With triethylamine; In dichloromethane; for 1h;

With citric acid; In dichloromethane; water;

Reference yield:

: C₁₀H₁₂O₄S

: 920-37-6
2-Chloroacrylonitrile

: 1356089-38-7
2-[4-((E)-2-cyano-ethenesulfonyl)phenyl]-2-methylpropionic acid

Guidance literature:: C₁₀H₁₂O₄S; 2-Chloroacrylonitrile; With acetic acid; In methanol; at 20 ℃;

With triethylamine; In methanol;
DOI:10.1021/jm501437v