Ethyl 2-(3-amino-2-oxo-1,2-dihydropyridin-1-yl)acetate

Base Information

Chemical Name:Ethyl 2-(3-amino-2-oxo-1,2-dihydropyridin-1-yl)acetate
CAS No.:147283-74-7
Molecular Formula:C9H12N2O3
Molecular Weight:196.206
Hs Code.:
DSSTox Substance ID:DTXSID00434487
Nikkaji Number:J2.529.204I
Wikidata:Q82248922
Mol file:147283-74-7.mol

Synonyms:147283-74-7;ethyl 2-(3-amino-2-oxo-1,2-dihydropyridin-1-yl)acetate;ETHYL 2-(3-AMINO-2-OXOPYRIDIN-1-YL)ACETATE;ETHYL (3-AMINO-2-OXO-1,2-DIHYDROPYRIDYL)ACETATE;Ethyl (3-amino-2-oxopyridin-1(2H)-yl)acetate;SCHEMBL3911656;DTXSID00434487;BQWBDOJVEUYSPH-UHFFFAOYSA-N;AKOS011381069;AT13458;FT-0653437;EN300-117540;ethyl(3-amino-2-oxo-1,2-dihydropyridyl)acetate;A808627;2-(3-amino-2-oxo-1-pyridinyl)acetic acid ethyl ester;ethyl2-(3-amino-2-oxo-1,2-dihydropyridin-1-yl)acetate;Z955149982;ethyl 2-(3-azanyl-2-oxidanylidene-pyridin-1-yl)ethanoate;2-Oxo-3-amino-1,2-dihydropyridine-1-acetic acid ethyl ester

Suppliers and Price of Ethyl 2-(3-amino-2-oxo-1,2-dihydropyridin-1-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ETHYL 2-(3-AMINO-2-OXOPYRIDIN-1(2H)-YL)ACETATE 95.00%
5G
$ 909.56

AK Scientific
Ethyl2-(3-amino-2-oxo-1,2-dihydropyridin-1-yl)acetate
2.5g
$ 1609.00

AK Scientific
Ethyl2-(3-amino-2-oxo-1,2-dihydropyridin-1-yl)acetate
250mg
$ 424.00

AK Scientific
Ethyl2-(3-amino-2-oxo-1,2-dihydropyridin-1-yl)acetate
100mg
$ 328.00

Total 5 raw suppliers

Chemical Property of Ethyl 2-(3-amino-2-oxo-1,2-dihydropyridin-1-yl)acetate

Chemical Property:

PSA：74.32000
LogP:0.57480
XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:196.08479225
Heavy Atom Count:14
Complexity:307

Purity/Quality:

97% ^*data from raw suppliers

ETHYL 2-(3-AMINO-2-OXOPYRIDIN-1(2H)-YL)ACETATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CN1C=CC=C(C1=O)N

Technology Process of Ethyl 2-(3-amino-2-oxo-1,2-dihydropyridin-1-yl)acetate

There total 4 articles about Ethyl 2-(3-amino-2-oxo-1,2-dihydropyridin-1-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 147283-76-9
ethyl 3-nitro-2-oxo-1,2-dihydro-1-pyridylacetate

: 147283-74-7
ethyl 3-amino-2-oxo-1,2-dihydro-1-pyridylacetate

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In ethanol; for 16h;

Reference yield:

: 6332-56-5
3-nitropyridone

: 147283-74-7
ethyl 3-amino-2-oxo-1,2-dihydro-1-pyridylacetate

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / tetrahydrofuran / 15 h / 55 °C

2: H₂ / PtO₂ / ethanol

With hydrogen; sodium hydride; platinum(IV) oxide; In tetrahydrofuran; ethanol;
DOI:10.1016/S0960-894X(03)00254-3

Reference yield:

: 6332-56-5
2-hydroxy-3-nitropyridine

: 147283-74-7
ethyl 3-amino-2-oxo-1,2-dihydro-1-pyridylacetate

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaH / tetrahydrofuran / -78 °C

1.2: tetrahydrofuran

2.1: H₂ / Pd/C / methanol / 2068.59 Torr

With hydrogen; sodium hydride; palladium on activated charcoal; In tetrahydrofuran; methanol;
DOI:10.1016/S0960-894X(02)01037-5