(4-{2-[(tert-butyldimethylsilyl)oxy]ethyl}phenyl)boronic acid

Base Information

Chemical Name:(4-{2-[(tert-butyldimethylsilyl)oxy]ethyl}phenyl)boronic acid
CAS No.:1035099-75-2
Molecular Formula:C₁₄H₂₅BO₃Si
Molecular Weight:280.247
Hs Code.:
Mol file:1035099-75-2.mol

Synonyms:(4-{2-[(tert-butyldimethylsilyl)oxy]ethyl}phenyl)boronic acid

Suppliers and Price of (4-{2-[(tert-butyldimethylsilyl)oxy]ethyl}phenyl)boronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 6 raw suppliers

Chemical Property of (4-{2-[(tert-butyldimethylsilyl)oxy]ethyl}phenyl)boronic acid

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (4-{2-[(tert-butyldimethylsilyl)oxy]ethyl}phenyl)boronic acid

There total 1 articles about (4-{2-[(tert-butyldimethylsilyl)oxy]ethyl}phenyl)boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 73899-15-7
1-(t-butyldimethylsilyloxy)-2-(4-bromophenyl)ethane

: 1035099-75-2
(4-{2-[(tert-butyldimethylsilyl)oxy]ethyl}phenyl)boronic acid

Guidance literature:: 1-(t-butyldimethylsilyloxy)-2-(4-bromophenyl)ethane; With n-butyllithium; In tetrahydrofuran; hexanes; at -78 ℃; for 1.5h;

With Triisopropyl borate; In tetrahydrofuran; hexanes; at -78 - 20 ℃; for 3h;

With hydrogenchloride; In tetrahydrofuran; hexanes; water;

Reference yield:

: 1035099-75-2
(4-{2-[(tert-butyldimethylsilyl)oxy]ethyl}phenyl)boronic acid

: 1181691-10-0
2-(6-bromo-3,4-dihydroisoquinolin-2(1H)-yl)-2-oxoethyl acetate

: 1181691-11-1
2-hydroxy-1-(6-(4-(2-hydroxyethyl)phenyl)-3,4-dihydroisoquinolin-2(1H)-yl)ethanone

Guidance literature:: With sodium hydrogencarbonate; In ethanol; benzene; at 100 ℃; for 3h; Inert atmosphere; Microwave irradiation;

Reference yield:

: 1035099-75-2
(4-{2-[(tert-butyldimethylsilyl)oxy]ethyl}phenyl)boronic acid

: 1426536-78-8
C₃₂H₃₆N₂O₄Si

Guidance literature:: Multi-step reaction with 2 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium phosphate / tetrahydrofuran / 15 h / 80 °C

2: triethylamine / dichloromethane / 40 °C

With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In tetrahydrofuran; dichloromethane; 1: |Suzuki Coupling;
DOI:10.1021/ml4000832