2-Fluoro-6-hydroxyphenylboronic acid

Base Information

Chemical Name:2-Fluoro-6-hydroxyphenylboronic acid
CAS No.:1256345-60-4
Molecular Formula:C6H6BFO3
Molecular Weight:155.921
Hs Code.:2931900090
European Community (EC) Number:815-950-9
DSSTox Substance ID:DTXSID80681533
Wikidata:Q82605607
Mol file:1256345-60-4.mol

Synonyms:1256345-60-4;2-FLUORO-6-HYDROXYPHENYLBORONIC ACID;(2-Fluoro-6-hydroxyphenyl)boronic acid;MFCD17214242;(2-Fluoro-6-hydroxyphenyl)boronicacid;AMY165;SCHEMBL15475873;DTXSID80681533;FPXQHZPCFRQWCP-UHFFFAOYSA-N;ZB0260;AKOS015853280;DS-17595;SY226646;CS-0043300;Boronic acid, B-(2-fluoro-6-hydroxyphenyl)-;W13758;A890145

Suppliers and Price of 2-Fluoro-6-hydroxyphenylboronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Fluoro-6-hydroxyphenylboronicAcid
250mg
$ 90.00

SynQuest Laboratories
2-Fluoro-6-hydroxyphenylboronic acid
250 mg
$ 151.00

SynQuest Laboratories
2-Fluoro-6-hydroxyphenylboronic acid
1 g
$ 301.00

Crysdot
(2-Fluoro-6-hydroxyphenyl)boronicacid 95+%
25g
$ 310.00

Crysdot
(2-Fluoro-6-hydroxyphenyl)boronicacid 95+%
10g
$ 145.00

Chemenu
(2-Fluoro-6-hydroxyphenyl)boronicacid 95+%
25g
$ 140.00

Ambeed
(2-Fluoro-6-hydroxyphenyl)boronicacid 95%
10g
$ 137.00

Ambeed
(2-Fluoro-6-hydroxyphenyl)boronicacid 95%
5g
$ 72.00

Ambeed
(2-Fluoro-6-hydroxyphenyl)boronicacid 95%
1g
$ 19.00

Ambeed
(2-Fluoro-6-hydroxyphenyl)boronicacid 95%
250mg
$ 12.00

Total 42 raw suppliers

Chemical Property of 2-Fluoro-6-hydroxyphenylboronic acid

Chemical Property:

Boiling Point:333.3±52.0 °C(Predicted)
PKA:8.40±0.58(Predicted)
PSA：60.69000
Density:1.42±0.1 g/cm3(Predicted)
LogP:-0.78890
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:DMSO (Slightly), Methanol (Slightly)
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:156.0394024
Heavy Atom Count:11
Complexity:133

Purity/Quality:

99%, ^*data from raw suppliers

2-Fluoro-6-hydroxyphenylboronicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=C(C=CC=C1F)O)(O)O
Uses 2-Fluoro-6-hydroxyphenylboronic Acid is a synthetic reagent used in the preparation of alkylene-bridged [(3,4-dihydro-2H-benzo[b][1,4]oxazinyl) or (piperidinyl)(biphenyl-3-yl)pyrazolo[1,5-a]pyrimidinyl](tert-butoxy)acetic acid derivatives as HIV integrase inhibitors for treating HIV infection.

Technology Process of 2-Fluoro-6-hydroxyphenylboronic acid

There total 6 articles about 2-Fluoro-6-hydroxyphenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1-(1-ethoxyethoxy)-3-fluorobenzene

: 1256345-60-4
(2-fluoro-6-hydroxy-phenyl)boronic acid

Guidance literature:: 1-(1-ethoxyethoxy)-3-fluorobenzene; With n-butyllithium; In tetrahydrofuran; at -80 - -70 ℃; for 1.5h; Inert atmosphere;

With Trimethyl borate; In tetrahydrofuran; for 2h;

Reference yield: 50.0%

: 185913-28-4
2-(3-fluorophenoxy)tetrahydro-2H-pyran

: 1256345-60-4
(2-fluoro-6-hydroxy-phenyl)boronic acid

Guidance literature:: 2-(3-fluorophenoxy)tetrahydro-2H-pyran; With n-butyllithium; In tetrahydrofuran; at -80 - -70 ℃; for 1.5h; Inert atmosphere;

With Trimethyl borate; In tetrahydrofuran; for 2h;